Evidence map›Paper›PMID 37631271›Full record

ArticlePharmaceutics2023

Polymeric Patches Based on Chitosan/Green Clay Composites and Hazelnut Shell Extract as Bio-Sustainable Medication for Wounds.

Carmen Laura Pérez Gutíerrez, Alessandro Di Michele, Cinzia Pagano, Debora Puglia, Francesca Luzi, Tommaso Beccari, Maria Rachele Ceccarini, Sara Primavilla, Andrea Valiani, Camilla Vicino and 3 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 9 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Carmen Laura Pérez GutíerrezDepartment of Pharmaceutical Sciences, University of Perugia, 06123 Perugia, Italy.
Alessandro Di MicheleDepartment of Physics and Geology, University of Perugia, 06123 Perugia, Italy.ORCID 0000-0002-0357-2608
Cinzia PaganoDepartment of Pharmaceutical Sciences, University of Perugia, 06123 Perugia, Italy.ORCID 0000-0003-0827-9299
Debora PugliaDepartment of Civil and Environmental Engineering, University of Perugia, UdR INSTM, 05100 Terni, Italy.ORCID 0000-0001-8515-7813
Francesca LuziDepartment of Materials, Environmental Sciences and Urban Planning (SIMAU), Polytechnic University of Marche, 60131 Ancona, Italy.ORCID 0000-0001-8785-5033
Tommaso BeccariDepartment of Pharmaceutical Sciences, University of Perugia, 06123 Perugia, Italy.ORCID 0000-0001-9637-6579
Maria Rachele CeccariniDepartment of Pharmaceutical Sciences, University of Perugia, 06123 Perugia, Italy.ORCID 0000-0002-5344-4890
Sara PrimavillaIstituto Zooprofilattico Sperimentale dell'Umbria e delle Marche "Togo Rosati", 06126 Perugia, Italy.ORCID 0000-0002-5711-3685
Andrea ValianiIstituto Zooprofilattico Sperimentale dell'Umbria e delle Marche "Togo Rosati", 06126 Perugia, Italy.
Camilla VicinoDepartment of Pharmaceutical Sciences, University of Perugia, 06123 Perugia, Italy.ORCID 0000-0002-8042-8044
Maurizio RicciDepartment of Pharmaceutical Sciences, University of Perugia, 06123 Perugia, Italy.ORCID 0000-0002-3373-9771
César Antonio Viseras IborraDepartment of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Granada, 18016 Granada, Spain.ORCID 0000-0002-2219-3566
Luana PerioliDepartment of Pharmaceutical Sciences, University of Perugia, 06123 Perugia, Italy.ORCID 0000-0003-3890-3283
University of Perugia · ITIstituto Zooprofilattico Sperimentale dell'Umbria e delle Marche · ITUniversidad de Granada · ESMarche Polytechnic University · IT

Funding

European Union - NextGenerationEU under the Italian Ministry of University and Re-search (MUR) National Innovation Ecosystem ECS00000041 - VITALITY
6 · The paper itself

Abstract

Hazelnut shells, the main waste deriving from hazelnut processing, represent an interesting source of active molecules useful in pharmaceutics, although they have not yet been examined in depth. A hydrosoluble extract (hazelnut shell extract, HSE) was prepared by the maceration method using a hydroalcoholic solution and used as the active ingredient of patches (prepared by casting method) consisting of composites of highly deacetylated chitosan and green clay. In vitro studies showed that the formulation containing HSE is able to stimulate keratinocyte growth, which is useful for healing purposes, and to inhibit the growth of

Indexed as

bioadhesionchitosangreen clayhazelnut shell extractsustainabilitywounds

Identifiers

PMID37631271
PMCPMC10459527
OpenAlexW4385428640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.