Evidence map›Paper›PMID 37631219›Full record

ReviewPlants (Basel, Switzerland)2023

Hansen Solubility Parameters Applied to the Extraction of Phytochemicals.

Fábio Junior Moreira Novaes, Daliane Cláudia de Faria, Fabio Zamboni Ferraz, Francisco Radler de Aquino Neto

Abstract readReview
In one paragraph

Review in Plants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Phytochemistry and In Vitro Bioactivities ofMolecules (Basel, Switzerland) · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fábio Junior Moreira NovaesDepartamento de Química, Universidade Federal de Viçosa, Avenida Peter Henry Rolfs, s/n, Campus Universitário, Viçosa 36570-900, MG, Brazil.ORCID 0000-0003-2849-7875
Daliane Cláudia de FariaDepartamento de Química, Universidade Federal de Viçosa, Avenida Peter Henry Rolfs, s/n, Campus Universitário, Viçosa 36570-900, MG, Brazil.
Fabio Zamboni FerrazDepartamento de Química, Universidade Federal de Viçosa, Avenida Peter Henry Rolfs, s/n, Campus Universitário, Viçosa 36570-900, MG, Brazil.
Francisco Radler de Aquino NetoLaboratório de Apoio ao Desenvolvimento Tecnológico (LADETEC/IQ-UFRJ), Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-598, RJ, Brazil.ORCID 0000-0003-2374-9228

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior Finance Code 001Fundação de Amparo à Pesquisa do Estado de Minas Gerais APQ-01574-22 and RED-00144-22National Council for Scientific and Technological Development
6 · The paper itself

Abstract

In many analytical chemical procedures, organic solvents are required to favour a better global yield upon the separation, extraction, or isolation of the target phytochemical analyte. The selection of extraction solvents is generally based on the solubility difference between target analytes and the undesired matrix components, as well as the overall extraction procedure cost and safety. Hansen Solubility Parameters are typically used for this purpose. They are based on the product of three coordinated forces (hydrogen bonds, dispersion, and dipolar forces) calculated for any substance to predict the miscibility of a compound in a pure solvent, in a mixture of solvents, or in non-solvent compounds, saving time and costs on method development based on a scientific understanding of chemical composition and intermolecular interactions. This review summarises how Hansen Solubility Parameters have been incorporated into the classical and emerging (or greener) extraction techniques of phytochemicals as an alternative to trial-and-error approaches, avoiding impractical experimental conditions and resulting in, for example, saving resources and avoiding unnecessary solvent wasting.

Indexed as

alternative solventsanalytical green chemistry strategygroup contribution methodpredictive solubility modelsolvent selection

Identifiers

PMID37631219
PMCPMC10459436

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.