Evidence map›Paper›PMID 37630978›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

Photodynamic Antimicrobial Activity of a Novel 5,10,15,20-Tetrakis (4-Ethylphenyl) Porphyrin against Clinically Important Bacteria.

Fabián Espitia-Almeida, Roger Valle-Molinares, Elkin Navarro Quiroz, Leonardo C Pacheco-Londoño, Nataly J Galán-Freyle

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Fabián Espitia-AlmeidaLife Science Research Center, Universidad Simón Bolívar, Barranquilla 080002, Colombia.ORCID 0000-0001-9885-5071
Roger Valle-MolinaresFaculty of Basic Sciences, Biology Program, Universidad del Atlántico, Puerto Colombia 081001, Colombia.ORCID 0000-0002-8003-4221
Elkin Navarro QuirozLife Science Research Center, Universidad Simón Bolívar, Barranquilla 080002, Colombia.ORCID 0000-0001-7567-6409
Leonardo C Pacheco-LondoñoLife Science Research Center, Universidad Simón Bolívar, Barranquilla 080002, Colombia.
Nataly J Galán-FreyleLife Science Research Center, Universidad Simón Bolívar, Barranquilla 080002, Colombia.
Universidad Simón Bolívar · COUniversity of Atlántico · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The growing emergence of microbes resistant to commercially available antibiotic therapies poses a threat to healthcare systems worldwide. Multiple factors have been associated with the increasing incidence of hospital-acquired infections caused by antibiotic-resistant pathogens, including the indiscriminate use of broad-spectrum antibiotics, the massive application of antibiotics in hospitals as a prophylactic measure, self-medication, and nonadherence to pharmacological therapies by patients. In this study, we developed a novel treatment to mitigate the impact of microbial resistance. We synthesized a benzoporphyrin derivative, 5,10,15,20-tetrakis (4-ethylphenyl) porphyrin (TEtPP), with a reaction yield close to 50%. TEtPP exhibited excellent photophysical properties (Φ

Indexed as

antimicrobial activityMRSAphotodynamicphotophysical propertiesporphyrinPseudomonas aeruginosaStaphylococcus aureus

Identifiers

PMID37630978
PMCPMC10459089
OpenAlexW4385364239

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.