Evidence map›Paper›PMID 37630835›Full record

Trial reportNutrients2023

Interactions between Mediterranean Diet Supplemented with Dairy Foods and the Gut Microbiota Influence Cardiovascular Health in an Australian Population.

Jocelyn M Choo, Karen J Murphy, Alexandra T Wade, Yanan Wang, Ella L Bracci, Courtney R Davis, Kathryn A Dyer, Richard J Woodman, Jonathan M Hodgson, Geraint B Rogers

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 4 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 4 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Diets to promote healthy brain ageing.Nature reviews. Neurology · 2025
    Review
  13. Review
  14. Gut microbiota: a potential new regulator of hypertension.Frontiers in cardiovascular medicine · 2024
    Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Jocelyn M ChooMicrobiome Research and Host Health, Lifelong Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5001, Australia.
Karen J MurphyAlliance for Research in Exercise, Nutrition and Activity, University of South Australia, GPO Box 2471, Adelaide, SA 5001, Australia.ORCID 0000-0002-2589-1319
Alexandra T WadeAlliance for Research in Exercise, Nutrition and Activity, University of South Australia, GPO Box 2471, Adelaide, SA 5001, Australia.
Yanan WangCSIRO MOSH-Future Science Platform, Health & Biosecurity, Adelaide, SA 5001, Australia.
Ella L BracciAlliance for Research in Exercise, Nutrition and Activity, University of South Australia, GPO Box 2471, Adelaide, SA 5001, Australia.ORCID 0000-0001-7319-027X
Courtney R DavisAlliance for Research in Exercise, Nutrition and Activity, University of South Australia, GPO Box 2471, Adelaide, SA 5001, Australia.ORCID 0000-0002-3866-2603
Kathryn A DyerClinical and Health Sciences, University of South Australia, GPO Box 2471, Adelaide, SA 5001, Australia.ORCID 0000-0003-4785-4962
Richard J WoodmanFlinders Centre for Epidemiology and Biostatistics, Flinders University, GPO Box 2100, Adelaide, SA 5001, Australia.ORCID 0000-0002-4094-1222
Jonathan M HodgsonNutrition and Health Innovation Research Institute, School of Medical and Health Sciences, Edith Cowan University, Perth, WA 6027, Australia.ORCID 0000-0001-6184-7764
Geraint B RogersMicrobiome Research and Host Health, Lifelong Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5001, Australia.
University of South Australia · AUFlinders University · AUCSIRO Health and Biosecurity · AUEdith Cowan University · AU

Funding

Australian Government Research Training Program (RTP)Dairy AustraliaRoyal Perth Hospital Medical Research Foundation Fellowship
6 · The paper itself

Abstract

The impact of a Mediterranean diet on the intestinal microbiome has been linked to its health benefits. We aim to evaluate the effects of a Mediterranean diet supplemented with dairy foods on the gut microbiome in Australians at risk of cardiovascular disease. In a randomised controlled cross-over study, 34 adults with a systolic blood pressure ≥120 mmHg and with risk factors for cardiovascular disease were randomly allocated to a Mediterranean diet with 3-4 daily serves of dairy foods (Australian recommended daily intake (RDI) of 1000-1300 mg per day (MedDairy)) or a low-fat (LFD) control diet. Between each 8-week diet, participants underwent an 8-week washout period. Microbiota characteristics of stool samples collected at the start and end of each diet period were determined by 16S rRNA amplicon sequencing. MedDairy-associated effects on bacterial relative abundance were correlated with clinical, anthropometric, and cognitive outcomes. No change in the overall faecal microbial structure or composition was observed with either diet (

Indexed as

Cardiovascular DiseasesDiet, MediterraneanGastrointestinal MicrobiomeHypotensionAdultAustraliaClostridiaceaeCross-Over StudiesDietary SupplementsHumansRNA, Ribosomal, 16SRNA, Ribosomal, 16Sclinical trialdairy foodsgut microbiomeMediterranean diet

Identifiers

PMID37630835
PMCPMC10459086
OpenAlexW4386030131

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.