Evidence map›Paper›PMID 37630732›Full record

ArticleNutrients2023

Dietary Flaxseed and Flaxseed Oil Differentially Modulate Aspects of the Microbiota Gut-Brain Axis Following an Acute Lipopolysaccharide Challenge in Male C57Bl/6 Mice.

Dawson B H Livingston, Allison Sweet, Alexane Rodrigue, Lalit Kishore, Julia Loftus, Farida Ghali, Salma Mahmoodianfard, Colleen Celton, Farah Hosseinian, Krista A Power

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Regulating the crosstalk betweenFrontiers in immunology · 2026
    Review
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  7. Foods (Basel, Switzerland) · 2024
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Dawson B H LivingstonFaculty of Medicine, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON K1H 8L1, Canada.ORCID 0000-0001-7197-9146
Allison SweetFaculty of Medicine, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON K1H 8L1, Canada.ORCID 0009-0002-4044-1380
Alexane RodrigueFaculty of Medicine, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON K1H 8L1, Canada.
Lalit KishoreFaculty of Health Science, School of Nutrition Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada.
Julia LoftusFaculty of Science, Department of Biochemistry, University of Ottawa, Ottawa, ON K1N 6N5, Canada.ORCID 0009-0005-3293-9789
Farida GhaliFaculty of Health Science, School of Nutrition Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada.
Salma MahmoodianfardFaculty of Health Science, School of Human Kinetics, University of Ottawa, Ottawa, ON K1N 6N5, Canada.ORCID 0000-0002-9603-2001
Colleen CeltonFaculty of Science, Department of Chemistry, Carleton University, Ottawa, ON K1S 5B6, Canada.
Farah HosseinianFaculty of Science, Department of Chemistry, Carleton University, Ottawa, ON K1S 5B6, Canada.
Krista A PowerFaculty of Medicine, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON K1H 8L1, Canada.ORCID 0000-0002-7575-3918
University of Ottawa · CACarleton University · CA

Funding

Natural Sciences and Engineering Research Council 2018-06545
6 · The paper itself

Abstract

The microbiota gut-brain axis (mGBA) is an important contributor to mental health and neurological and mood disorders. Lipopolysaccharides (LPS) are endotoxins that are components of Gram-negative bacteria cell walls and have been widely shown to induce both systemic and neuro-inflammation. Flaxseed (

Indexed as

FlaxGastrointestinal MicrobiomeAnimalsBrain-Gut AxisDietInterleukin-10Linseed OilLipopolysaccharidesMaleMiceMitoguazoneTumor Necrosis Factor-alphaInterleukin-10Linseed OilLipopolysaccharidesmethylglyoxal bis(3-aminopropylamidinohydrazone)MitoguazoneTumor Necrosis Factor-alphaflaxseedflaxseed oilgut–brain axisinflammationlipopolysaccharideLPSmicrobiotamicrobiota gut–brain axisPICRUSt2Qiime2

Identifiers

PMID37630732
PMCPMC10459276
OpenAlexW4385760273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.