Evidence map›Paper›PMID 37630601›Full record

ArticleMicroorganisms2023

Early Detection of the Recombinant SARS-CoV-2 XAN Variant in Bulgaria: Initial Genomic Insights into Yet Another Piece of the Growing Puzzle of Recombinant Clades.

Ivailo Alexiev, Ivan Ivanov, Marta Giovanetti, Eleonora Cella, Ivan Stoikov, Deyan Donchev, Lyubomira Grigorova, Anna Gancheva, Reneta Dimitrova, Fabio Scarpa and 6 more

Abstract read
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ivailo AlexievNational Center of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.ORCID 0000-0002-3186-1124
Ivan IvanovNational Center of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.ORCID 0000-0002-2616-894X
Marta GiovanettiInstituto Rene Rachou Fundação Oswaldo Cruz, Belo Horizonte 30190-009, Minas Gerais, Brazil.ORCID 0000-0002-5849-7326
Eleonora CellaBurnett School of Biomedical Sciences, University of Central Florida, Orlando, FL 32816, USA.ORCID 0000-0002-7870-9744
Ivan StoikovNational Center of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.ORCID 0000-0002-9924-8553
Deyan DonchevNational Center of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.ORCID 0000-0001-7447-7627
Lyubomira GrigorovaNational Center of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.
Anna GanchevaNational Center of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.
Reneta DimitrovaNational Center of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.ORCID 0000-0001-7711-6798
Fabio ScarpaDepartment of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-3501-714X
Neli KorsunNational Center of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.ORCID 0000-0002-3188-2283
Ivelina TrifonovaNational Center of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.ORCID 0000-0002-4543-6831
Veselin DobrinovNational Center of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.
Todor KantardjievNational Center of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.
Iva ChristovaNational Center of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.
Massimo CiccozziUnit of Medical Statistics and Molecular Epidemiology, Università Campus Bio-Medico di Roma, 00128 Rome, Italy.ORCID 0000-0003-3866-9239

Funding

European Regional Development Fund through Operational Program Science and Education for Smart Growth 2014-2020 BG05M2OP001-1.002-0001-C04Ministry of Education and Science KП-06-H43/1-27.11.2020PON "Ricerca e Innovazione" 2014-2020 NA
6 · The paper itself

Abstract

The first recombinant SARS-CoV-2 variants were identified in 2022, causing public health concerns. The importance of recombinant variants has increased especially since the WHO designated the recombinant variant XBB and its lineages as subvariants that require monitoring on 20 November 2022. In this study, we provide the first insights into the new SARS-CoV-2 variant named XAN, a recombinant composed of Omicron sub-lineages BA.2 and BA.5. To our knowledge, this is the first report on the recombinant SARS-CoV-2 XAN variant identified in Bulgaria.

Indexed as

BA.2BA.5coronavirusCOVID-19 pandemicmolecular datingOmicron variantphylogenomicsrecombinant SARS-CoV-2XAN

Identifiers

PMID37630601
PMCPMC10457977

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.