Evidence map›Paper›PMID 37630388›Full record

ArticleMolecules (Basel, Switzerland)2023

The Mechanism of Anti-Tumor Activity of 6-Morpholino- and 6-Amino-9-Sulfonylpurine Derivatives on Human Leukemia Cells.

Marijana Leventić, Teuta Opačak-Bernardi, Vesna Rastija, Josipa Matić, Dijana Pavlović Saftić, Željka Ban, Biserka Žinić, Ljubica Glavaš-Obrovac

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Marijana LeventićDepartment of Medicinal Chemistry, Biochemistry and Laboratory Medicine, Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Huttlerova 4, 31000 Osijek, Croatia.ORCID 0000-0002-3326-4868
Teuta Opačak-BernardiDepartment of Medicinal Chemistry, Biochemistry and Laboratory Medicine, Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Huttlerova 4, 31000 Osijek, Croatia.ORCID 0000-0001-8563-8684
Vesna RastijaDepartment of Agroecology and Environmental Protection, Faculty of Agrobiotechnical Sciences Osijek, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, Croatia.ORCID 0000-0001-9542-4022
Josipa MatićLaboratory for Biomolecular Interactions and Spectroscopy, Division of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Bijenička Cesta 54, 10000 Zagreb, Croatia.ORCID 0000-0003-1774-0446
Dijana Pavlović SaftićLaboratory for Biomolecular Interactions and Spectroscopy, Division of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Bijenička Cesta 54, 10000 Zagreb, Croatia.ORCID 0000-0002-0657-1635
Željka BanLaboratory for Biomolecular Interactions and Spectroscopy, Division of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Bijenička Cesta 54, 10000 Zagreb, Croatia.ORCID 0000-0002-6723-5811
Biserka ŽinićLaboratory for Biomolecular Interactions and Spectroscopy, Division of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Bijenička Cesta 54, 10000 Zagreb, Croatia.ORCID 0000-0002-1536-7142
Ljubica Glavaš-ObrovacDepartment of Medicinal Chemistry, Biochemistry and Laboratory Medicine, Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Huttlerova 4, 31000 Osijek, Croatia.ORCID 0000-0001-7497-296X
Ruđer Bošković Institute · HRUniversity of Osijek · HR

Funding

Croatian Science Foundation HRZZ-1477Faculty of Medicine, Josip Juraj Strossmayer University of Osijek IP-06-2018
6 · The paper itself

Abstract

The aim of this study was to explore the mechanism of antitumor effect of (

Indexed as

LeukemiaMicroRNAsCaspase 3Cytochromes cHumansMorpholinosProto-Oncogene Proteins c-aktCaspase 3Cytochromes cMicroRNAsMorpholinosProto-Oncogene Proteins c-aktADMET propertiesanti-tumorapoptosisgene expressionleukemia cellsmiRNA expressionN-9-sulfonylpurines

Identifiers

PMID37630388
PMCPMC10458232
OpenAlexW4386030303

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.