Evidence map›Paper›PMID 37630337›Full record

ReviewMolecules (Basel, Switzerland)2023

Medical Applications and Advancement of Near Infrared Photosensitive Indocyanine Green Molecules.

Zulpya Mahmut, Chunmei Zhang, Fei Ruan, Nan Shi, Xinyao Zhang, Yuda Wang, Xianhong Zheng, Zixin Tang, Biao Dong, Donghui Gao and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
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  5. FeiScience · 2026
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  11. Review
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  13. Review
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  15. Review
  16. Article
  17. Indocyanine green fluorescence in parathyroidectomy: enhancing efficiency through real-time adenoma identification.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Zulpya MahmutDepartment of Cell Biology and Medical Genetics, College of Basic Medical Science, Jilin University, Changchun 130021, China.
Chunmei ZhangDepartment of Cell Biology and Medical Genetics, College of Basic Medical Science, Jilin University, Changchun 130021, China.
Fei RuanState Key Laboratory on Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun 130012, China.
Nan ShiDepartment of Respiratory Medicine, No. 964 Hospital of People's Liberation Army, 4799 Xi'an Road, Changchun 130062, China.
Xinyao ZhangDepartment of Cell Biology and Medical Genetics, College of Basic Medical Science, Jilin University, Changchun 130021, China.
Yuda WangDepartment of Cell Biology and Medical Genetics, College of Basic Medical Science, Jilin University, Changchun 130021, China.
Xianhong ZhengDepartment of Cell Biology and Medical Genetics, College of Basic Medical Science, Jilin University, Changchun 130021, China.
Zixin TangState Key Laboratory on Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun 130012, China.
Biao DongState Key Laboratory on Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun 130012, China.
Donghui GaoDepartment of Anesthesiology and Operating Room, School and Hospital of Stomatology, Jilin University, Changchun 130012, China.
Jiao SunDepartment of Cell Biology and Medical Genetics, College of Basic Medical Science, Jilin University, Changchun 130021, China.ORCID 0000-0003-3868-368X
Jilin University · CN

Funding

Collaborative Innovation Special Science and Technology Assistance Program 2022E02130National Natural Science Foundation of China 52250077
6 · The paper itself

Abstract

Indocyanine green (ICG) is an important kind of near infrared (NIR) photosensitive molecules for PTT/PDT therapy as well as imaging. When exposed to NIR light, ICG can produce reactive oxygen species (ROS), which can kill cancer cells and pathogenic bacteria. Moreover, the absorbed light can also be converted into heat by ICG molecules to eliminate cancer cells. In addition, it performs exceptionally well in optical imaging-guided tumor therapy and antimicrobial therapy due to its deeper tissue penetration and low photobleaching properties in the near-infrared region compared to other dyes. In order to solve the problems of water and optical stability and multi-function problem of ICG molecules, composite nanomaterials based on ICG have been designed and widely used, especially in the fields of tumors and sterilization. So far, ICG molecules and their composite materials have become one of the most famous infrared sensitive materials. However, there have been no corresponding review articles focused on ICG molecules. In this review, the molecular structure and properties of ICG, composite material design, and near-infrared light- triggered anti-tumor, and antibacterial, and clinical applications are reviewed in detail, which of great significance for related research.

Indexed as

Dermatitis, PhototoxicIndocyanine GreenAnti-Bacterial AgentsColoring AgentsHot TemperatureHumansAnti-Bacterial AgentsColoring AgentsIndocyanine Greenantibacterial treatmentcomposite nanoparticlesICGlight therapytumor treatment

Identifiers

PMID37630337
PMCPMC10459369
OpenAlexW4385873765

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.