Evidence map›Paper›PMID 37630304›Full record

ArticleMolecules (Basel, Switzerland)2023

Structure Activity Relationship and Molecular Docking of Some Quinazolines Bearing Sulfamerazine Moiety as New 3CLpro, cPLA2, sPLA2 Inhibitors.

Mohammed Abdalla Hussein, Rita M Borik, Mohamed S Nafie, Heba M Abo-Salem, Sylvia A Boshra, Zahraa N Mohamed

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Mohammed Abdalla HusseinBiotechnology Department, Faculty of Applied Heath Science Technology, October 6 University, Giza 28125, Egypt.ORCID 0000-0002-1811-2794
Rita M BorikChemistry Department, Faculty of Science (Female Section), Jazan University, Jazan 82621, Saudi Arabia.
Mohamed S NafieChemistry Department (Biochemistry Program), Faculty of Science, Suez Canal University, Ismailia 41522, Egypt.ORCID 0000-0003-4454-6390
Heba M Abo-SalemChemistry of Natural Compounds Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre, Giza 28125, Egypt.ORCID 0000-0003-3778-2272
Sylvia A BoshraDepartment of Biochemistry, Faculty of Pharmacy, October 6 University, Giza 28125, Egypt.ORCID 0000-0003-4059-2912
Zahraa N MohamedMedical Laboratory Department, Faculty of Applied Medical Sciences, October 6 University, Giza 28125, Egypt.
October 6 University · EGJazan University · SANational Research Centre · EGSuez Canal University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current work was conducted to synthesize several novel anti-inflammatory quinazolines having sulfamerazine moieties as new 3CLpro, cPLA2, and sPLA2 inhibitors. The thioureido derivative

Indexed as

COVID-19HumansIvermectinMolecular Docking SimulationPhospholipases A2, CytosolicSARS-CoV-2Structure-Activity RelationshipSulfamerazineIvermectinPhospholipases A2, CytosolicSulfamerazine3CLprocPLA2IL-8quinazolinessPLA2sulfamerazineTNF-α inhibitors

Identifiers

PMID37630304
PMCPMC10460087
OpenAlexW4385805664

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.