Evidence map›Paper›PMID 37630260›Full record

ArticleMolecules (Basel, Switzerland)2023

The Amoebicidal Activity of Diferrocenyl Derivatives: A Significant Dependence on the Electronic Environment.

Yanis Toledano-Magaña, Mario Néquiz, Lucía Margarita Valenzuela-Salas, Jessica J Sánchez-García, Rodrigo Galindo-Murillo, Juan Carlos García-Ramos, Elena I Klimova

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Yanis Toledano-MagañaEscuela de Ciencias de la Salud, Universidad Autónoma de Baja California, Ensenada 22860, Mexico.ORCID 0000-0002-2595-7939
Mario NéquizUnidad de Investigación en Medicina Experimental, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 06726, Mexico.ORCID 0000-0003-2818-2267
Lucía Margarita Valenzuela-SalasFacultad de Ciencias de la Salud Unidad Valle de las Palmas, Universidad Autónoma de Baja California, Tijuana 22260, Mexico.ORCID 0000-0002-2226-0431
Jessica J Sánchez-GarcíaFacultad de Química, Universidad Nacional Autónoma de México, Ciudad Universitaria, Mexico City 04510, Mexico.ORCID 0000-0003-4719-0924
Rodrigo Galindo-MurilloDepartment of Medicinal Chemistry, College of Pharmacy, University of Utah, Salt Lake City, UT 84112, USA.ORCID 0000-0001-5847-4143
Juan Carlos García-RamosEscuela de Ciencias de la Salud, Universidad Autónoma de Baja California, Ensenada 22860, Mexico.ORCID 0000-0001-9861-2467
Elena I KlimovaFacultad de Química, Universidad Nacional Autónoma de México, Ciudad Universitaria, Mexico City 04510, Mexico.ORCID 0000-0001-9232-1001
Universidad Autónoma de Baja California · MXUniversidad Nacional Autónoma de México · MXUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amoebiasis is the second leading cause of death worldwide associated with parasitic disease and is becoming a critical health problem in low-income countries, urging new treatment alternatives. One of the most promising strategies is enhancing the redox imbalance within these susceptible parasites related to their limited antioxidant defense system. Metal-based drugs represent a perfect option due to their extraordinary capacity to stabilize different oxidation states and adopt diverse geometries, allowing their interaction with several molecular targets. This work describes the amoebicidal activity of five 2-(

Indexed as

AmebicidesEntamoeba histolyticaAntioxidantsElectronicsAmebicidesAntioxidantsamoebiasisantiproliferative activitydiferrocenyl derivativeselectronic propertiesmetal-based drugs

Identifiers

PMID37630260
PMCPMC10458203
OpenAlexW4385758871

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.