Evidence map›Paper›PMID 37630113›Full record

ArticleMicromachines2023

Structural Optimization Design of Microfluidic Chips Based on Fast Sequence Pair Algorithm.

Chuang Wu, Jiju Sun, Haithm Yahya Mohammed Almuaalemi, A S M Muhtasim Fuad Sohan, Binfeng Yin

Abstract read
In one paragraph

Article in Micromachines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chuang WuSchool of Mechanical Engineering, Yangzhou University, Yangzhou 225127, China.ORCID 0000-0002-8247-6680
Jiju SunSchool of Mechanical Engineering, Yangzhou University, Yangzhou 225127, China.
Haithm Yahya Mohammed AlmuaalemiSchool of Mechanical Engineering, Yangzhou University, Yangzhou 225127, China.ORCID 0009-0000-1958-9802
A S M Muhtasim Fuad SohanFaculty of Engineering, Department of Mechanical Engineering, University of Adelaide, Adelaide, SA 5000, Australia.ORCID 0000-0002-0490-1119
Binfeng YinSchool of Mechanical Engineering, Yangzhou University, Yangzhou 225127, China.ORCID 0000-0002-0484-4951

Funding

"Green Yang Golden Phoenix Project" in Yangzhou City YZLYJFJH2021YXBS098Innovative Science and Technology Platform Project of Cooperation between Yangzhou City and Yangzhou University YZ2020266Jiangsu Agricultural Science and Technology Innovation Fund CX(21)3162Market Supervision Administration Science and Technology Fund of Jiangsu Province KJ2023076National Natural Science Foundation of China 52075138Natural Science Foundation of the Jiangsu Higher Education Institutions of China 22KJB150050Science and Technology Planning Project of Yangzhou City YZ2022180
6 · The paper itself

Abstract

The market for microfluidic chips is experiencing significant growth; however, their development is hindered by a complex design process and low efficiency. Enhancing microfluidic chips' design quality and efficiency has emerged as an integral approach to foster their advancement. Currently, the existing structural design schemes lack careful consideration regarding the impact of chip area, microchannel length, and the number of intersections on chip design. This inadequacy leads to redundant chip structures resulting from the separation of layout and wiring design. This study proposes a structural optimization method for microfluidic chips to address these issues utilizing a simulated annealing algorithm. The simulated annealing algorithm generates an initial solution in advance using the fast sequence pair algorithm. Subsequently, an improved simulated annealing algorithm is employed to obtain the optimal solution for the device layout. During the wiring stage, an advanced wiring method is used to designate the high wiring area, thereby increasing the success rate of microfluidic chip wiring. Furthermore, the connection between layout and routing is reinforced through an improved layout adjustment method, which reduces the length of microchannels and the number of intersections. Finally, the effectiveness of the structural optimization approach is validated through six sets of test cases, successfully achieving the objective of enhancing the design quality of microfluidic chips.

Indexed as

fast sequence pair algorithmmicrofluidic chipoptimization algorithmsimulated annealing algorithmstructural design

Identifiers

PMID37630113
PMCPMC10456452

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.