Evidence map›Paper›PMID 37629640›Full record

ReviewLife (Basel, Switzerland)2023

Focused Ultrasound, an Emerging Tool for Atherosclerosis Treatment: A Comprehensive Review.

Cynthia Imtiaz, Muhammad Awais Farooqi, Theophilus Bhatti, Jooho Lee, Ramsha Moin, Chul Ung Kang, Hafiz Muhammad Umer Farooqi

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Cynthia ImtiazOcean and Biomedical Ultrasound Laboratory, Department of Ocean System Engineering, Jeju National University, Jeju-si 63243, Republic of Korea.
Muhammad Awais FarooqiDepartment of Mechatronics Engineering, Jeju National University, Jeju-si 63243, Republic of Korea.ORCID 0000-0002-8035-9296
Theophilus BhattiInterdisciplinary Department of Advanced Convergence Technology and Science, College of Pharmacy, Jeju National University, Jeju 63243, Republic of Korea.ORCID 0000-0003-4914-0656
Jooho LeeOcean and Biomedical Ultrasound Laboratory, Department of Ocean System Engineering, Jeju National University, Jeju-si 63243, Republic of Korea.ORCID 0000-0002-4580-5633
Ramsha MoinDepartment of Pediatrics, Elaj Hospital, Gujranwala 52250, Pakistan.
Chul Ung KangDepartment of Mechatronics Engineering, Jeju National University, Jeju-si 63243, Republic of Korea.
Hafiz Muhammad Umer FarooqiBoard of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.ORCID 0000-0002-1735-5911
Jeju National University · KRCedars-Sinai Medical Center · USGIFT University · PK

Funding

Jeju National University 2023
6 · The paper itself

Abstract

Focused ultrasound (FUS) has emerged as a promising noninvasive therapeutic modality for treating atherosclerotic arterial disease. High-intensity focused ultrasound (HIFU), a noninvasive and precise modality that generates high temperatures at specific target sites within tissues, has shown promising results in reducing plaque burden and improving vascular function. While low-intensity focused ultrasound (LIFU) operates at lower energy levels, promoting mild hyperthermia and stimulating tissue repair processes. This review article provides an overview of the current state of HIFU and LIFU in treating atherosclerosis. It focuses primarily on the therapeutic potential of HIFU due to its higher penetration and ability to achieve atheroma disruption. The review summarizes findings from animal models and human trials, covering the effects of FUS on arterial plaque and arterial wall thrombolysis in carotid, coronary and peripheral arteries. This review also highlights the potential benefits of focused ultrasound, including its noninvasiveness, precise targeting, and real-time monitoring capabilities, making it an attractive approach for the treatment of atherosclerosis and emphasizes the need for further investigations to optimize FUS parameters and advance its clinical application in managing atherosclerotic arterial disease.

Indexed as

atherosclerosisfocused ultrasoundhigh-intensity focused ultrasoundlow-intensity focused ultrasoundthrombolysis

Identifiers

PMID37629640
PMCPMC10455721
OpenAlexW4386032684

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.