ArticleLife (Basel, Switzerland)2023
A Food Matrix Triggers a Similar Allergic Immune Response in BALB/c Mice Sensitized with Native, Denatured, and Digested Ovalbumin.
Jesús Gilberto Arámburo-Gálvez, Raúl Tinoco-Narez-Gil, Aldo Alejandro Arvizu-Flores, Oscar Gerardo Figueroa-Salcido, José Antonio Mora-Melgem, Alma Rosa Islas-Rubio, Lilian Karem Flores-Mendoza, Veronica Lopez-Teros, Humberto Astiazaran-Garcia, Feliznando Isidro Cárdenas-Torres and 1 more
Open access · goldAbstract read
In one paragraphArticle in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
11 authors at 2 institutions in 1 country.
Jesús Gilberto Arámburo-GálvezGraduate Program in Health Sciences, Faculty of Biological and Health Sciences, Universidad de Sonora, Hermosillo 83000, Sonora, Mexico.ORCID 0000-0002-6977-5651 Raúl Tinoco-Narez-GilNutrition Sciences Graduate Program, Faculty of Nutrition Sciences, Autonomous University of Sinaloa, Culiacan 80019, Sinaloa, Mexico.
Aldo Alejandro Arvizu-FloresGraduate Program in Health Sciences, Faculty of Biological and Health Sciences, Universidad de Sonora, Hermosillo 83000, Sonora, Mexico.
Oscar Gerardo Figueroa-SalcidoNutrition Sciences Graduate Program, Faculty of Nutrition Sciences, Autonomous University of Sinaloa, Culiacan 80019, Sinaloa, Mexico.ORCID 0000-0003-4276-8715 José Antonio Mora-MelgemNutrition Sciences Graduate Program, Faculty of Nutrition Sciences, Autonomous University of Sinaloa, Culiacan 80019, Sinaloa, Mexico.
Alma Rosa Islas-RubioDepartment of Plant-Origin Food Technology, Research Center for Food and Development, CIAD, A.C. Carretera Gustavo Enrique Astiazarán Rosas, No. 46 Col. La Victoria, Hermosillo 83304, Sonora, Mexico.
Lilian Karem Flores-MendozaClinical and Research Laboratory (LACIUS, C.N.), Department of Chemical, Biological, and Agricultural Sciences (DC-QB), Faculty of Biological and Health Sciences, University of Sonora, Navojoa 85880, Sonora, Mexico.
Veronica Lopez-TerosGraduate Program in Health Sciences, Faculty of Biological and Health Sciences, Universidad de Sonora, Hermosillo 83000, Sonora, Mexico.ORCID 0000-0003-1429-4911 Humberto Astiazaran-GarciaGraduate Program in Health Sciences, Faculty of Biological and Health Sciences, Universidad de Sonora, Hermosillo 83000, Sonora, Mexico.ORCID 0000-0002-2452-0057 Feliznando Isidro Cárdenas-TorresGraduate Program in Health Sciences, Faculty of Biological and Health Sciences, Universidad de Sonora, Hermosillo 83000, Sonora, Mexico.ORCID 0000-0002-4434-0459 Noé OntiverosClinical and Research Laboratory (LACIUS, C.N.), Department of Chemical, Biological, and Agricultural Sciences (DC-QB), Faculty of Biological and Health Sciences, University of Sonora, Navojoa 85880, Sonora, Mexico.ORCID 0000-0001-8678-0447 Universidad de Sonora · MXUniversidad Autónoma de Sinaloa · MX
Funding
PROFAPI 2022 PRO_A3_023
6 · The paper itselfAbstract
The search for an animal model to evaluate the allergenic potential of processed food products is still ongoing. Both the sensitization to ovalbumin (OVA) in different structural states and the allergic response triggered after intragastric or food challenges were assessed. BALB/c mice were sensitized intraperitoneally to OVA (50 µg) in different structural states (native OVA, N-OVA; denatured OVA, D-OVA; formaldehyde- and lysine-treated OVA, FK-OVA; denatured OVA-FK, OVA-DFK; peptides from pepsin digestion, Pep-OVA). Anti-OVA-specific IgE responses were evaluated using ELISA. Anaphylactic signs and mMCP-1 serum levels were evaluated after intragastric (2.0 mg/OVA) and food (0.41 mg/OVA) challenges. IgE reactivities to N-OVA and D-OVA were similar among groups (
Indexed as
allergic reactionfood allergyfood matrixovalbumin
Identifiers
PMID37629590
PMCPMC10455175
OpenAlexW4385805655
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