Evidence map›Paper›PMID 37629557›Full record

ReviewLife (Basel, Switzerland)2023

Chronic Prostatitis/Chronic Pain Pelvic Syndrome and Male Infertility.

Andrea Graziani, Giuseppe Grande, Michel Martin, Giordana Ferraioli, Elena Colonnello, Massimo Iafrate, Fabrizio Dal Moro, Alberto Ferlin

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
11.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Andrea GrazianiUnit of Andrology and Reproductive Medicine, Department of Medicine, University of Padova, 35122 Padova, Italy.ORCID 0000-0002-3239-2374
Giuseppe GrandeUnit of Andrology and Reproductive Medicine, Department of Medicine, University of Padova, 35122 Padova, Italy.ORCID 0000-0003-3264-0937
Michel MartinUnit of Andrology and Reproductive Medicine, Department of Medicine, University of Padova, 35122 Padova, Italy.
Giordana FerraioliUrology Clinic, Department of Surgery, Oncology and Gastroenterology, University of Padova, 35122 Padova, Italy.
Elena ColonnelloDepartment of Experimental Medicine, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-0081-7163
Massimo IafrateUrology Clinic, Department of Surgery, Oncology and Gastroenterology, University of Padova, 35122 Padova, Italy.ORCID 0000-0001-5940-1683
Fabrizio Dal MoroUrology Clinic, Department of Surgery, Oncology and Gastroenterology, University of Padova, 35122 Padova, Italy.
Alberto FerlinUnit of Andrology and Reproductive Medicine, Department of Medicine, University of Padova, 35122 Padova, Italy.ORCID 0000-0001-5817-8141
University of Padua · ITUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is defined as urologic pain or discomfort in the pelvic region, associated with urinary symptoms and/or sexual dysfunction, lasting for at least 3 of the previous 6 months. The rate of symptoms related to prostatitis has a mean prevalence of 8-8.2%. CP/CPPS is most frequent in men younger than 50 years, among whom it is the most common urologic diagnosis. In the last decades, many studies have been published on CP/CPPS and its association with male infertility. The pathophysiologic relation between CP/CPPS and male infertility involves several aspects, which are not well studied yet. A reduction in semen parameters has been demonstrated in patients with CP/CPPS, and several mechanisms have been proposed to represent putative pathophysiological links between CP/CPPS and infertility, including male accessory gland inflammation, metabolic syndrome, inflammatory bowel disease, HPV co-infection and autoimmunity. In light of this evidence, a multidisciplinary approach is advocated for patients with known CP/CPPS, and particular attention is needed for male patients of infertile couples in order to evaluate male accessory glands correctly. In addition, it is advisable that future studies dealing with the treatment of CP/CPPS take into consideration all the different pathophysiological aspects implicated.

Indexed as

chronic pelvic pain syndromechronic prostatitismale infertility

Identifiers

PMID37629557
PMCPMC10455764
OpenAlexW4385636951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.