Evidence map›Paper›PMID 37629474›Full record

ReviewJournal of clinical medicine2023

Radiomics and Artificial Intelligence for the Diagnosis and Monitoring of Alzheimer's Disease: A Systematic Review of Studies in the Field.

Roberta Bevilacqua, Federico Barbarossa, Lorenzo Fantechi, Daniela Fornarelli, Enrico Paci, Silvia Bolognini, Cinzia Giammarchi, Fabrizia Lattanzio, Lucia Paciaroni, Giovanni Renato Riccardi and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Integrated cerebellar radiomic-network model for predicting mild cognitive impairment in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Roberta BevilacquaScientific Direction, IRCCS INRCA, 60124 Ancona, Italy.
Federico BarbarossaScientific Direction, IRCCS INRCA, 60124 Ancona, Italy.
Lorenzo FantechiUnit of Nuclear Medicine, IRCCS INRCA, 60127 Ancona, Italy.ORCID 0000-0002-7379-7714
Daniela FornarelliUnit of Nuclear Medicine, IRCCS INRCA, 60127 Ancona, Italy.
Enrico PaciUnit of Radiology, IRCCS INRCA, 60127 Ancona, Italy.ORCID 0000-0003-3448-9345
Silvia BologniniScientific Direction, IRCCS INRCA, 60124 Ancona, Italy.
Cinzia GiammarchiScientific Direction, IRCCS INRCA, 60124 Ancona, Italy.
Fabrizia LattanzioScientific Direction, IRCCS INRCA, 60124 Ancona, Italy.
Lucia PaciaroniUnit of Neurology, IRCCS INRCA, 60127 Ancona, Italy.ORCID 0000-0003-2574-4105
Giovanni Renato RiccardiClinical Unit of Physical Rehabilitation, IRCCS INRCA, 60127 Ancona, Italy.
Giuseppe PelliccioniUnit of Neurology, IRCCS INRCA, 60127 Ancona, Italy.ORCID 0000-0002-0377-9713
Leonardo BiscettiUnit of Neurology, IRCCS INRCA, 60127 Ancona, Italy.
Elvira MaranesiScientific Direction, IRCCS INRCA, 60124 Ancona, Italy.ORCID 0000-0002-2414-3773
Istituti di Ricovero e Cura a Carattere Scientifico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of radiomics and artificial intelligence applied for the diagnosis and monitoring of Alzheimer's disease has developed in recent years. However, this approach is not yet completely applicable in clinical practice. The aim of this paper is to provide a systematic analysis of the studies that have included the use of radiomics from different imaging techniques and artificial intelligence for the diagnosis and monitoring of Alzheimer's disease in order to improve the clinical outcomes and quality of life of older patients. A systematic review of the literature was conducted in February 2023, analyzing manuscripts and articles of the last 5 years from the PubMed, Scopus and Embase databases. All studies concerning discrimination among Alzheimer's disease, Mild Cognitive Impairment and healthy older people performing radiomics analysis through machine and deep learning were included. A total of 15 papers were included. The results showed a very good performance of this approach in the differentiating Alzheimer's disease patients-both at the dementia and pre-dementia phases of the disease-from healthy older people. In summary, radiomics and AI can be valuable tools for diagnosing and monitoring the progression of Alzheimer's disease, potentially leading to earlier and more accurate diagnosis and treatment. However, the results reported by this review should be read with great caution, keeping in mind that imaging alone is not enough to identify dementia due to Alzheimer's.

Indexed as

Alzheimerartificial intelligencedeep learningdiagnosismachine learningMCIolder peopleradiomicssystematic review

Identifiers

PMID37629474
PMCPMC10455452
OpenAlexW4386049657

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.