Evidence map›Paper›PMID 37629454›Full record

ArticleJournal of clinical medicine2023

Osteophyte Bridge Formation Correlates with Vascular Calcification and Cardiovascular Disease in Diffuse Idiopathic Skeletal Hyperostosis.

Ryosuke Hirota, Atsushi Teramoto, Mitsunori Yoshimoto, Hiroyuki Takashima, Naomi Yasuda, Arihiko Tsukamoto, Noriyuki Iesato, Makoto Emori, Kousuke Iba, Nobuyoshi Kawaharada and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. The relation between cardiovascular calcifications and diffuse idiopathic skeletal hyperostosis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Ryosuke HirotaDepartment of Orthopaedic Surgery, School of Medicine, Sapporo Medical University, Sapporo 060-8556, Japan.
Atsushi TeramotoDepartment of Orthopaedic Surgery, School of Medicine, Sapporo Medical University, Sapporo 060-8556, Japan.ORCID 0000-0002-4860-9259
Mitsunori YoshimotoDepartment of Orthopaedic Surgery, School of Medicine, Sapporo Medical University, Sapporo 060-8556, Japan.
Hiroyuki TakashimaFaculty of Health Sciences, Hokkaido University, Sapporo 060-0808, Japan.
Naomi YasudaDepartment of Cardiovascular Surgery, School of Medicine, Sapporo Medical University, Sapporo 060-8556, Japan.ORCID 0000-0002-1283-2459
Arihiko TsukamotoDepartment of Orthopaedic Surgery, School of Medicine, Sapporo Medical University, Sapporo 060-8556, Japan.
Noriyuki IesatoDepartment of Orthopaedic Surgery, School of Medicine, Sapporo Medical University, Sapporo 060-8556, Japan.
Makoto EmoriDepartment of Orthopaedic Surgery, School of Medicine, Sapporo Medical University, Sapporo 060-8556, Japan.
Kousuke IbaDepartment of Orthopaedic Surgery, School of Medicine, Sapporo Medical University, Sapporo 060-8556, Japan.
Nobuyoshi KawaharadaDepartment of Cardiovascular Surgery, School of Medicine, Sapporo Medical University, Sapporo 060-8556, Japan.
Toshihiko YamashitaDepartment of Orthopaedic Surgery, School of Medicine, Sapporo Medical University, Sapporo 060-8556, Japan.
Sapporo Medical University · JPSapporo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diffuse idiopathic skeletal hyperostosis (DISH) is a noninflammatory spondyloarthropathy characterized by ectopic calcification of spinal cord tissue. Its etiology is possibly polygenic. However, its pathogenesis and systemic effects remain unclear. Recent studies have reported a high prevalence of DISH in heart failure patients. The authors investigated how the incidence and severity of DISH are associated with vascular calcification and the occurrence of cardiovascular events. In this retrospective chart review study, 500 patients with cardiovascular disease who underwent surgery (cardiovascular events group) and 500 patients with non-cardiovascular disease who underwent computed tomography scans (non-cardiovascular events group) were randomly selected to investigate the degree of ossification of the anterior longitudinal ligament and the incidence of DISH. We found that the incidence of DISH was higher in patients with cardiovascular events and that patients with DISH had more calcification of the coronary arteries and aorta. Next, we examined the relationship between the degree of coronary and aortic calcification, the incidence of DISH, and the degree of ossification of the anterior longitudinal ligament in the non-cardiovascular event group. The prevalence of DISH in the cardiovascular and non-cardiovascular groups was 31.4% and 16.5%, respectively (

Indexed as

cardiovascular diseasediffuse idiopathic skeletal hyperostosisvascular calcification

Identifiers

PMID37629454
PMCPMC10455897
OpenAlexW4386028606

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.