Evidence map›Paper›PMID 37629431›Full record

ArticleJournal of clinical medicine2023

Endometriosis and Adverse Pregnancy Outcomes: A Nationwide Population-Based Study.

Hee Jeung Lim, Jiyu Sun, Banhyang Min, Myungeun Song, Tae Hun Kim, Byoung Jae Kim, Kyu Ri Hwang, Taek Sang Lee, Hye Won Jeon, Sun Min Kim

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Hee Jeung LimDepartment of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
Jiyu SunIntegrated Biostatistics Branch, Division of Cancer Data Science, National Cancer Center, Goyang-si 10408, Republic of Korea.ORCID 0000-0002-4010-2023
Banhyang MinDepartment of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
Myungeun SongDepartment of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
Tae Hun KimDepartment of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.ORCID 0000-0003-3198-0788
Byoung Jae KimDepartment of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
Kyu Ri HwangDepartment of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
Taek Sang LeeDepartment of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
Hye Won JeonDepartment of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
Sun Min KimDepartment of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.ORCID 0000-0002-3369-3937
Seoul National University · KRNational Cancer Center · KR

Funding

focused clinical research grant-in-aid from the Seoul Metropolitan Government-Seoul National University 04-2021-0018the New Faculty Startup Fund from Seoul National University 800-20230290
6 · The paper itself

Abstract

Endometriosis is a major cause of infertility, and considering its pathophysiology, it is expected to affect pregnancy outcomes as well. This study aimed to evaluate whether endometriosis is associated with adverse pregnancy outcomes after successful conception. Data from singleton pregnancy deliveries between January 2014 and October 2019 were obtained from the Korean Health Insurance Review and Assessment Service database. We compared the clinical characteristics and adverse pregnancy outcomes of women with and without endometriosis. A total of 1,251,597 pregnant women were enrolled; of these, 32,951 (2.6%) were assigned to the endometriosis group. Women with endometriosis had significantly more adverse pregnancy outcomes than those without endometriosis. Adverse pregnancy outcomes associated with endometriosis included preterm labor, preterm birth, preeclampsia, fetal growth restriction, placenta previa, placental abruption, antepartum and postpartum hemorrhage, and stillbirth. This study also showed an increased risk of postpartum hemorrhage, blood transfusion, uterine artery embolization, and cesarean hysterectomy in the endometriosis group compared to the non- endometriosis group. The cesarean delivery rate was significantly higher in the endometriosis group than in the non-endometriosis group, even after excluding cases of antenatal obstetric complications that could increase the risk of cesarean delivery. Women with endometriosis not only have difficulty conceiving, but also have a significantly higher risk of adverse pregnancy outcomes.

Indexed as

cesarean deliveryendometriosisplacental abruptionplacenta previapostpartum hemorrhagepreeclampsiapregnancy outcomestillbirth

Identifiers

PMID37629431
PMCPMC10455587
OpenAlexW4386030473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.