ArticleJournal of clinical medicine2023
Lung Transplantation Outcomes in Recipients Aged 70 Years or Older and the Impact of Center Volume.
Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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Who cites it
5 citing papers in PubMed.
- Lung transplantation outcomes in candidates aged ≥ 70 years old: A 10-year single center experience.JHLT open · 2026Article
- Pulmonary indications for heart-lung transplantation: A modified Delphi survey among the French transplantation community.JHLT open · 2026Review
- Long-term outcomes of lung transplantation in the elderly: an analysis using the UNOS database.Journal of thoracic disease · 2026Article
- The Role of Vaccination in Adult Solid Organ Transplantation: Updated Reviews with Recent Guidelines.Microorganisms · 2026Review
- ERS International Congress 2023: highlights from the Thoracic Surgery and Lung Transplantation Assembly.ERJ open research · 2024Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate trends and outcomes of lung transplants (LTx) in recipients ≥ 70 years.
methodsWe performed a retrospective analysis of the UNOS database identifying all patients undergoing LTx (May 2005-December 2022). Baseline characteristics and postoperative outcomes were compared by age (<70 years, ≥70 years) and center volume. Kaplan-Meier analyses were performed with pairwise comparisons between subgroups.
results34,957 patients underwent LTx, of which 3236 (9.3%) were ≥70 years. The rate of LTx in recipients ≥ 70 has increased over time, particularly in low-volume centers (LVCs); consequently, high-volume centers (HVCs) and LVCs perform similar rates of LTx for recipients ≥ 70. Recipients ≥ 70 had higher rates of receiving from donor after circulatory death lungs and of extended donor criteria. Recipients ≥ 70 were more likely to die of cardiovascular diseases or malignancy, while recipients < 70 of chronic primary graft failure. Survival time was shorter for recipients ≥ 70 compared to recipients < 70 old (hazard ratio (HR): 1.36, 95% confidence interval (CI): 1.28-1.44,
conclusionsCareful consideration is needed for recipient ≥ 70 selection, donor assessment, and post-transplant care to improve outcomes. Further research should explore strategies that advance perioperative care in centers with low long-term survival for recipients ≥ 70.
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