ReviewJournal of clinical medicine2023
Surgical Management of Ovarian Endometrioma: Impact on Ovarian Reserve Parameters and Reproductive Outcomes.
Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The role of TGF-β superfamily in endometriosis: a systematic review.Frontiers in immunology · 2025Pooled it
- Ethanol sclerotherapy for management of endometriomas: an overview of systematic reviews.Frontiers in endocrinology · 2025Pooled it
- Article
- Impact of oral contraceptive treatment duration on ovarian reserve markers and pain in women with ovarian endometrioma: a retrospective cohort study.Journal of ovarian research · 2026Article
- Endometriosis and Fertility: A Practical Guide: Results of the Working Group of the Weissensee 2025 Workshop of the Scientific Endometriosis Foundation.Geburtshilfe und Frauenheilkunde · 2026Article
- The value of the AAGL staging system for predicting recurrence after conservative surgery for ovarian endometriomas.Reproductive biology and endocrinology : RB&E · 2026Article
- Surgical management of endometriosis: surgical techniques, adjuvant therapy, and long-term management Number 10 - 2026.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2026Review
- Direct IVF versus prior laparoscopic cystectomy for ovarian endometrioma ≥4 cm: cumulative live birth rate and implications for fertility preservation - a retrospective cohort study.Frontiers in endocrinology · 2026Article
- Identifying key determinants of cumulative live birth in women with ovarian endometrioma undergoing ethanol sclerotherapy followed byFrontiers in cell and developmental biology · 2026Article
- Diagnosis and management of endometriosis-associated infertility Number 4 - 2026.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2026Article
- The Impact of Endometriosis on Ovarian Reserve: A Systematic Review.International journal of women's health · 2026Review
- The Significance of Serum CA-125 Level on the Live Birth Rates of In Vitro Fertilisation in Women with Endometriosis.Medicina (Kaunas, Lithuania) · 2025Observational
- Never say never: the nuances of surgical counseling of patients with endometriomas and infertility.F&S reports · 2025Article
- Is the EMpressin Injection in ENDOmetrioma eXcision Surgery Useful? The EMENDOX Study.Journal of clinical medicine · 2025Article
- Balancing Decidualization, Autophagy, and Cellular Senescence for Reproductive Success in Endometriosis Biology.International journal of molecular sciences · 2025Review
- First birth and total fertility rate in women with surgically verified endometriosis - A nationwide register study of 18 320 women across reproductive life course.Acta obstetricia et gynecologica Scandinavica · 2025Article
- The impact of surgical intervention on time to conception and obstetric outcomes in women with endometriomas: a retrospective cohort study.BMC pregnancy and childbirth · 2025Article
- Evidence on Serum Anti-Müllerian Hormone Levels and Endometriosis Surgery.Journal of clinical medicine · 2025Review
- Future of Sclerotherapy in the Treatment of Endometriosis: A Narrative Literature Review.Cureus · 2025Review
- A Narrative Review Regarding Implication of Ovarian Endometriomas in Infertility.Life (Basel, Switzerland) · 2025Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ovarian endometriomas have a negative impact on a patient's reproductive potential and are likely to cause a reduction in ovarian reserve. The most commonly employed ovarian reserve parameters are anti-Müllerian hormone (AMH) and antral follicular count (AFC). Surgical management options of endometrioma include cystectomy, ablative methods, ethanol sclerotherapy and combined techniques. The optimal surgical approach remains a matter of debate. Our review aimed to summarize the literature on the impact of surgical management of endometrioma on AMH, AFC and fertility outcomes. Cystectomy may reduce recurrence rates and increase chances of spontaneous conception. However, a postoperative reduction in AMH is to be anticipated, despite there being evidence of recovery during follow-up. The reduction in ovarian reserve is likely multi-factorial. Cystectomy does not appear to significantly reduce, and may even increase, AFC. Ablative methods achieve an ovarian-tissue-sparing effect, and improved ovarian reserve, compared to cystectomy, has been demonstrated. A single study reported on AMH and AFC post sclerotherapy, and both were significantly reduced. AMH levels may be useful in predicting the chances of conception postoperatively. None of the aforementioned approaches has a clearly demonstrated superiority in terms of overall chances of conception. Surgical management of endometrioma may, overall, improve the probability of pregnancy. Evidence on its value before medically assisted reproduction (MAR) is conflicting; however, a combination of surgery followed by MAR may achieve the optimal fertility outcome. In view of the complexity of available evidence, individualization of care, combined with optimal surgical technique, is highly recommended.
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