Evidence map›Paper›PMID 37629137›Full record

ReviewInternational journal of molecular sciences2023

Prospects of Using Chitosan-Based Biopolymers in the Treatment of Peripheral Nerve Injuries.

Meng Zhang, Heng An, Fengshi Zhang, Haoran Jiang, Teng Wan, Yongqiang Wen, Na Han, Peixun Zhang

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. A review of new developments in peripheral nerve regeneration.Biochemistry and biophysics reports · 2026
    Review
  4. Article
  5. Article
  6. Special Issue "Synthesis, Properties and Applications of Polymers".International journal of molecular sciences · 2025
    Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Meng ZhangDepartment of Orthopedics and Trauma, Peking University People's Hospital, Beijing 100044, China.ORCID 0000-0002-1475-8133
Heng AnBeijing Key Laboratory for Bioengineering and Sensing Technology, Daxing Research Institute, School of Chemistry & Biological Engineering, University of Science & Technology Beijing, Beijing 100083, China.
Fengshi ZhangDepartment of Orthopedics and Trauma, Peking University People's Hospital, Beijing 100044, China.ORCID 0000-0003-2766-3974
Haoran JiangDepartment of Orthopedics and Trauma, Peking University People's Hospital, Beijing 100044, China.
Teng WanDepartment of Orthopedics and Trauma, Peking University People's Hospital, Beijing 100044, China.ORCID 0000-0002-0474-6534
Yongqiang WenBeijing Key Laboratory for Bioengineering and Sensing Technology, Daxing Research Institute, School of Chemistry & Biological Engineering, University of Science & Technology Beijing, Beijing 100083, China.ORCID 0000-0002-1924-4166
Na HanDepartment of Orthopedics and Trauma, Peking University People's Hospital, Beijing 100044, China.
Peixun ZhangDepartment of Orthopedics and Trauma, Peking University People's Hospital, Beijing 100044, China.
Peking University · CNUniversity of Science and Technology Beijing · CN

Funding

Beijing National Science Foundation 7212121Excellent Doctoral Graduate Innovation Foundation of Peking University Health Science CenterKey Laboratory of Trauma and Neural Regeneration (Peking University), Ministry of Education of China BMU2022JDJS008National Center for Trauma Medicine BMU2020XY005-01National Center for Trauma Medicine BMU2021XY008-01National Natural Science Foundation of China 21975019National Natural Science Foundation of China 22278003National Natural Science Foundation of China 52273120Peking University People's Hospital Research and Development Fund RDH2020-01Science Fund of Shandong Laboratory of Advanced Materials and Green Manufacturing (Yantai) AMGM2023F04
6 · The paper itself

Abstract

Peripheral nerve injuries are common neurological disorders, and the available treatment options, such as conservative management and surgical repair, often yield limited results. However, there is growing interest in the potential of using chitosan-based biopolymers as a novel therapeutic approach to treating these injuries. Chitosan-based biopolymers possess unique characteristics, including biocompatibility, biodegradability, and the ability to stimulate cell proliferation, making them highly suitable for repairing nerve defects and promoting nerve regeneration and functional recovery. Furthermore, these biopolymers can be utilized in drug delivery systems to control the release of therapeutic agents and facilitate the growth of nerve cells. This comprehensive review focuses on the latest advancements in utilizing chitosan-based biopolymers for peripheral nerve regeneration. By harnessing the potential of chitosan-based biopolymers, we can pave the way for innovative treatment strategies that significantly improve the outcomes of peripheral nerve injury repair, offering renewed hope and better prospects for patients in need.

Indexed as

ChitosanPeripheral Nerve InjuriesBiopolymersCell ProliferationConservative TreatmentHumansBiopolymersChitosancarbohydrate polymerschitosanchitosan-based biopolymersfunctionalized polymersperipheral nerve injury

Identifiers

PMID37629137
PMCPMC10454829
OpenAlexW4386029048

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.