Evidence map›Paper›PMID 37629132›Full record

ArticleInternational journal of molecular sciences2023

In Silico Analysis, Anticonvulsant Activity, and Toxicity Evaluation of Schisandrin B in Zebrafish Larvae and Mice.

Dorota Nieoczym, Nancy Saana Banono, Katarzyna Stępnik, Agnieszka A Kaczor, Przemysław Szybkowski, Camila Vicencio Esguerra, Wirginia Kukula-Koch, Kinga Gawel

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Dorota NieoczymDepartment of Animal Physiology and Pharmacology, Institute of Biological Sciences, Faculty of Biology and Biotechnology, Maria Curie-Skłodowska University, Akademicka 19, 20-033 Lublin, Poland.ORCID 0000-0002-9446-7343
Nancy Saana BanonoChemical Neuroscience Group, Centre for Molecular Medicine Norway, University of Oslo, Gaustadalleen 21, Forskningsparken, 0349 Oslo, Norway.ORCID 0000-0002-3061-1633
Katarzyna StępnikDepartment of Physical Chemistry, Institute of Chemical Sciences, Faculty of Chemistry, Maria Curie-Skłodowska University, Pl. M. Curie-Skłodowskiej 3/243, 20-031 Lublin, Poland.
Agnieszka A KaczorDepartment of Synthesis and Chemical Technology of Pharmaceutical Substances with Computer Modeling Laboratory, Faculty of Pharmacy, Medical University of Lublin, 4A Chodzki St., 20-093 Lublin, Poland.ORCID 0000-0001-8679-9623
Przemysław SzybkowskiDepartment of Experimental and Clinical Pharmacology, Medical University of Lublin, Jaczewskiego St. 8b, 20-090 Lublin, Poland.
Camila Vicencio EsguerraChemical Neuroscience Group, Centre for Molecular Medicine Norway, University of Oslo, Gaustadalleen 21, Forskningsparken, 0349 Oslo, Norway.
Wirginia Kukula-KochDepartment of Pharmacognosy with Medicinal Plants Garden, Medical University of Lublin, Chodźki St. 1, 20-093 Lublin, Poland.ORCID 0000-0001-7076-600X
Kinga GawelDepartment of Experimental and Clinical Pharmacology, Medical University of Lublin, Jaczewskiego St. 8b, 20-090 Lublin, Poland.ORCID 0000-0001-8857-847X
Medical University of Lublin · PLMaria Curie-Skłodowska University · PLUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study is to evaluate the anticonvulsant potential of schisandrin B, a main ingredient of

Indexed as

AnticonvulsantsZebrafishAnimalsCyclooctanesGlutamic AcidLarvaLignansMiceMolecular Docking SimulationPentylenetetrazolePolycyclic CompoundsReceptors, GABA-ASeizuresAnticonvulsantsCyclooctanesGlutamic AcidLignansPentylenetetrazolePolycyclic CompoundsReceptors, GABA-Aschizandrin Blocal field potential recordingsmicemolecular modelingpentylenetetrazoleschisandrin Bseizurestoxicityzebrafish

Identifiers

PMID37629132
PMCPMC10455331
OpenAlexW4386030267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.