Evidence map›Paper›PMID 37629117›Full record

ArticleInternational journal of molecular sciences2023

Anti-Glycolipid Antibody Examination in Five EAE Models and Theiler's Virus Model of Multiple Sclerosis: Detection of Anti-GM1, GM3, GM4, and Sulfatide Antibodies in Relapsing-Remitting EAE.

Kota Moriguchi, Yumina Nakamura, Ah-Mee Park, Fumitaka Sato, Motoi Kuwahara, Sundar Khadka, Seiichi Omura, Ijaz Ahmad, Susumu Kusunoki, Ikuo Tsunoda

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. The Safety ofViruses · 2026
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Kota MoriguchiDepartment of Microbiology, Faculty of Medicine, Kindai University, Osakasayama City 589-8511, Osaka, Japan.
Yumina NakamuraDepartment of Microbiology, Faculty of Medicine, Kindai University, Osakasayama City 589-8511, Osaka, Japan.
Ah-Mee ParkDepartment of Microbiology, Faculty of Medicine, Kindai University, Osakasayama City 589-8511, Osaka, Japan.
Fumitaka SatoDepartment of Microbiology, Faculty of Medicine, Kindai University, Osakasayama City 589-8511, Osaka, Japan.ORCID 0000-0001-6477-3457
Motoi KuwaharaDepartment of Neurology, Faculty of Medicine, Kindai University, Osakasayama City 589-8511, Osaka, Japan.
Sundar KhadkaDepartment of Microbiology, Faculty of Medicine, Kindai University, Osakasayama City 589-8511, Osaka, Japan.ORCID 0000-0002-5110-4446
Seiichi OmuraDepartment of Microbiology, Faculty of Medicine, Kindai University, Osakasayama City 589-8511, Osaka, Japan.ORCID 0000-0003-4619-9345
Ijaz AhmadDepartment of Microbiology, Faculty of Medicine, Kindai University, Osakasayama City 589-8511, Osaka, Japan.
Susumu KusunokiDepartment of Neurology, Faculty of Medicine, Kindai University, Osakasayama City 589-8511, Osaka, Japan.
Ikuo TsunodaDepartment of Microbiology, Faculty of Medicine, Kindai University, Osakasayama City 589-8511, Osaka, Japan.ORCID 0000-0003-1798-714X
Kindai University · JPDuke University · USJapan Community Healthcare Organization · JP

Funding

Japan Society for the Promotion of Science JP20K07455Japan Society for the Promotion of Science JP20K07894Japan Society for the Promotion of Science JP21K0287Japan Society for the Promotion of Science JP22K07527Japan Society for the Promotion of Science JP22K18378Japan Society for the Promotion of Science JP23K06493Kindai University All-Kindai University support project against COVID-19Kindai University Kindai University Research Enhancement Grant KD2303
6 · The paper itself

Abstract

Anti-glycolipid antibodies have been reported to play pathogenic roles in peripheral inflammatory neuropathies, such as Guillain-Barré syndrome. On the other hand, the role in multiple sclerosis (MS), inflammatory demyelinating disease in the central nervous system (CNS), is largely unknown, although the presence of anti-glycolipid antibodies was reported to differ among MS patients with relapsing-remitting (RR), primary progressive (PP), and secondary progressive (SP) disease courses. We investigated whether the induction of anti-glycolipid antibodies could differ among experimental MS models with distinct clinical courses, depending on induction methods. Using three mouse strains, SJL/J, C57BL/6, and A.SW mice, we induced five distinct experimental autoimmune encephalomyelitis (EAE) models with myelin oligodendrocyte glycoprotein (MOG)

Indexed as

Encephalomyelitis, Autoimmune, ExperimentalMultiple SclerosisTheilovirusAnimalsAntibodiesGlycolipidsMiceMice, Inbred C57BLMyelin-Oligodendrocyte GlycoproteinNeoplasm Recurrence, LocalSulfoglycosphingolipidsAntibodiesGlycolipidsMyelin-Oligodendrocyte GlycoproteinSulfoglycosphingolipidsanimal modelsautoimmunityCNS demyelinating diseasescytokinesenzyme-linked immunosorbent assayneuroimmunologyneuroinflammatory diseasesneurovirologyPicornaviridae infections

Identifiers

PMID37629117
PMCPMC10454742
OpenAlexW4385986708

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.