Evidence map›Paper›PMID 37629045›Full record

ArticleInternational journal of molecular sciences2023

Pharmacological Prevention of Ectopic Erythrophagocytosis by Cilostazol Mitigates Ferroptosis in NASH.

Joon Beom Park, Kangeun Ko, Yang Hyun Baek, Woo Young Kwon, Sunghwan Suh, Song-Hee Han, Yun Hak Kim, Hye Young Kim, Young Hyun Yoo

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Molecular and Immunometabolic Landscape of Erythrophagocytosis-induced Ferroptosis.Cardiovascular & hematological disorders drug targets · 2025
    Review
  8. Article
  9. Review
  10. Ferroptosis in organ fibrosis: From mechanisms to therapeutic medicines.Journal of translational internal medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Joon Beom ParkDepartment of Anatomy and Cell Biology, Dong-A University College of Medicine, Busan 49201, Republic of Korea.
Kangeun KoDepartment of Anatomy and Cell Biology, Dong-A University College of Medicine, Busan 49201, Republic of Korea.
Yang Hyun BaekDepartment of Gastroenterology, Dong-A University College of Medicine, Busan 49201, Republic of Korea.ORCID 0000-0002-9073-9233
Woo Young KwonDepartment of Anatomy and Cell Biology, Dong-A University College of Medicine, Busan 49201, Republic of Korea.
Sunghwan SuhDepartment of Endocrinology, Dong-A University College of Medicine, Busan 49201, Republic of Korea.
Song-Hee HanDepartment of Pathology, Dong-A University College of Medicine, Busan 49201, Republic of Korea.
Yun Hak KimDepartment of Anatomy, School of Medicine, Pusan National University, Yangsan 50612, Republic of Korea.ORCID 0000-0002-9796-8266
Hye Young KimDepartment of Anatomy, Inje University College of Medicine, Busan 47392, Republic of Korea.ORCID 0000-0002-8487-3655
Young Hyun YooDepartment of Anatomy and Cell Biology, Dong-A University College of Medicine, Busan 49201, Republic of Korea.ORCID 0000-0002-6809-6737
Dong-A University · KRInje University · KRPusan National University · KR

Funding

National Research Foundation of Korea NRF-2019R1A2C2002266National Research Foundation of Korea RS-2023-00248268
6 · The paper itself

Abstract

Hepatic iron overload (HIO) is a hallmark of nonalcoholic fatty liver disease (NAFLD) with a poor prognosis. Recently, the role of hepatic erythrophagocytosis in NAFLD is emerging as a cause of HIO. We undertook various assays using human NAFLD patient pathology samples and an in vivo nonalcoholic steatohepatitis (NASH) mouse model named STAM

Indexed as

FerroptosisNon-alcoholic Fatty Liver DiseaseAnimalsCilostazolHumansInflammationMiceCilostazolcilostazolerythrophagocytosisferroptosishepatic iron overloadNASH

Identifiers

PMID37629045
PMCPMC10454295
OpenAlexW4385877656

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.