Evidence map›Paper›PMID 37629011›Full record

ArticleInternational journal of molecular sciences2023

Predictive Genetic Biomarkers for the Development of Peritoneal Metastases in Colorectal Cancer.

Danique J I Heuvelings, Anne G W E Wintjens, Laura Moonen, Sanne M E Engelen, Ignace H J T de Hingh, Liselot B Valkenburg-van Iersel, Marcel den Dulk, Jan Beckervordersandforth, Sharon G M Thijssen, Daphne J G Leunissen and 5 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. The emerging role and mechanism of HMGA2 in breast cancer.Journal of cancer research and clinical oncology · 2024
    Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 2 countries.

Danique J I HeuvelingsNUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, 6229 ER Maastricht, The Netherlands.ORCID 0000-0001-5352-8704
Anne G W E WintjensNUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, 6229 ER Maastricht, The Netherlands.
Laura MoonenGROW School for Oncology and Reproduction, Maastricht University, 6229 ER Maastricht, The Netherlands.ORCID 0000-0003-3699-2534
Sanne M E EngelenDepartment of General Surgery, Maastricht University Medical Center (MUMC+), 6229 HX Maastricht, The Netherlands.
Ignace H J T de HinghGROW School for Oncology and Reproduction, Maastricht University, 6229 ER Maastricht, The Netherlands.
Liselot B Valkenburg-van IerselGROW School for Oncology and Reproduction, Maastricht University, 6229 ER Maastricht, The Netherlands.
Marcel den DulkNUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, 6229 ER Maastricht, The Netherlands.ORCID 0000-0002-6161-161X
Jan BeckervordersandforthDepartment of Pathology, Maastricht University Medical Center (MUMC+), 6229 HX Maastricht, The Netherlands.
Sharon G M ThijssenDepartment of Pathology, Maastricht University Medical Center (MUMC+), 6229 HX Maastricht, The Netherlands.
Daphne J G LeunissenGROW School for Oncology and Reproduction, Maastricht University, 6229 ER Maastricht, The Netherlands.
Laurents P S StassenNUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, 6229 ER Maastricht, The Netherlands.
Daniel KeszthelyiDivision of Gastroenterology and Hepatology, Maastricht University Medical Center (MUMC+), 6229 HX Maastricht, The Netherlands.
Zlatan MujagicDivision of Gastroenterology and Hepatology, Maastricht University Medical Center (MUMC+), 6229 HX Maastricht, The Netherlands.
Ernst-Jan M SpeelGROW School for Oncology and Reproduction, Maastricht University, 6229 ER Maastricht, The Netherlands.ORCID 0000-0002-3016-2989
Nicole D BouvyNUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, 6229 ER Maastricht, The Netherlands.
Maastricht University · NLRadboud University Nijmegen · NL

Funding

De stichting Stichting Jules Coenegracht Sr. not applicable
6 · The paper itself

Abstract

Metastatic colorectal cancer (CRC) is a common cause of cancer-related mortality, of which peritoneal metastases (PMs) have the worse outcome. Metastasis-specific markers may help predict the spread of tumor cells and select patients for preventive strategies. This exploratory pilot study aimed to gain more insight into genetic alterations in primary CRC tumors, which might be a predictive factor for the development of PM. Forty patients with T3 stage CRC were retrospectively divided in three groups: without metachronous metastases during 5-year follow-up (M0,

Indexed as

Colonic NeoplasmsPeritoneal NeoplasmsGenetic MarkersHumansPilot ProjectsProto-Oncogene Proteins B-rafRetrospective StudiesRNAGenetic MarkersProto-Oncogene Proteins B-rafRNAbiomarkerscolorectal cancergenetic mutationsnext generation sequencingperitoneal metastases

Identifiers

PMID37629011
PMCPMC10454220
OpenAlexW4385835405

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.