Evidence map›Paper›PMID 37628966›Full record

ArticleInternational journal of molecular sciences2023

Over-Expression of p190RhoGEF Regulates the Formation of Atherosclerotic Plaques in the Aorta of ApoE

So-Yeon Choi, Eun-Bi Lee, Jee-Hae Kim, Jong Ran Lee

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

So-Yeon ChoiDepartment of Bioinspired Science, The Graduate School, Ewha Womans University, Seoul 03760, Republic of Korea.
Eun-Bi LeeDepartment of Bioinspired Science, The Graduate School, Ewha Womans University, Seoul 03760, Republic of Korea.
Jee-Hae KimDepartment of Life Science, College of Natural Sciences, Ewha Womans University, Seoul 03760, Republic of Korea.
Jong Ran LeeDepartment of Life Science, College of Natural Sciences, Ewha Womans University, Seoul 03760, Republic of Korea.ORCID 0000-0001-5645-7075
Ewha Womans University · KR

Funding

National Research Foundation of Korea 2012R1A5A1048236, 2019R1A2C1007743
6 · The paper itself

Abstract

The RhoA-specific guanine nucleotide exchange factor p190RhoGEF has been implicated in the control of cell morphology, focal adhesion formation, and cell motility. Previously, we reported that p190RhoGEF is also active in various immune cells. In this study, we examined whether over-expression of p190RhoGEF could affect atherosclerotic plaque formation in mouse aortae. For that purpose, transgenic (TG) mice over-expressing p190RhoGEF were cross-bred with atherosclerosis-prone apolipoprotein E (ApoE)

Indexed as

AtherosclerosisPlaque, AtheroscleroticAnimalsAortaApolipoproteins ECytokinesMacrophagesMiceMice, TransgenicApolipoproteins ECytokinesApoE−/− miceatherosclerotic plaquesinflammatory cytokinesmacrophagep190RhoGEF

Identifiers

PMID37628966
PMCPMC10454661
OpenAlexW4385795809

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.