Evidence map›Paper›PMID 37628928›Full record

ArticleInternational journal of molecular sciences2023

Identification of an Additional Metal-Binding Site in Human Dipeptidyl Peptidase III.

Antonia Matić, Filip Šupljika, Hrvoje Brkić, Jasna Jurasović, Zrinka Karačić, Sanja Tomić

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Antonia MatićDivision of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Bijenička Cesta 54, 10000 Zagreb, Croatia.
Filip ŠupljikaDepartment of Chemistry and Biochemistry, Faculty of Food Technology and Biotechnology, Pierottijeva 6, 10000 Zagreb, Croatia.ORCID 0000-0001-8745-6956
Hrvoje BrkićFaculty of Medicine, J. J. Strossmayer University of Osijek, 31000 Osijek, Croatia.ORCID 0000-0001-6692-6875
Jasna JurasovićAnalytical Toxicology and Mineral Metabolism Unit, Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.ORCID 0000-0002-3183-7327
Zrinka KaračićDivision of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Bijenička Cesta 54, 10000 Zagreb, Croatia.ORCID 0000-0001-9643-4118
Sanja TomićDivision of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Bijenička Cesta 54, 10000 Zagreb, Croatia.ORCID 0000-0002-0550-0878
Ruđer Bošković Institute · HRInstitute for Medical Research and Occupational Health · HRUniversity of Osijek · HRUniversity of Zagreb · HR

Funding

Croatian Science Foundation IP-2018-01-2936
6 · The paper itself

Abstract

Dipeptidyl peptidase III (DPP III, EC 3.4.14.4) is a monozinc metalloexopeptidase that hydrolyzes dipeptides from the N-terminus of peptides consisting of three or more amino acids. Recently, DPP III has attracted great interest from scientists, and numerous studies have been conducted showing that it is involved in the regulation of various physiological processes. Since it is the only metalloenzyme among the dipeptidyl peptidases, we considered it important to study the process of binding and exchange of physiologically relevant metal dications in DPP III. Using fluorimetry, we measured the

Indexed as

Dipeptidyl-Peptidases and Tripeptidyl-PeptidasesBinding SitesCatalytic DomainHumansProtein Domainsdipeptidyl peptidase IIIDipeptidyl-Peptidases and Tripeptidyl-PeptidasesDPP3 protein, humanbinding affinitydipeptidyl peptidase IIImetal exchangemetal inhibitionmetal ions

Identifiers

PMID37628928
PMCPMC10454320
OpenAlexW4385795996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.