Evidence map›Paper›PMID 37628866›Full record

ArticleInternational journal of molecular sciences2023

Interferon Gamma Enhances Cytoprotective Pathways via Nrf2 and MnSOD Induction in Friedreich's Ataxia Cells.

Riccardo Luffarelli, Luca Panarello, Andrea Quatrana, Francesca Tiano, Silvia Fortuni, Alessandra Rufini, Florence Malisan, Roberto Testi, Ivano Condò

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Riccardo LuffarelliDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.
Luca PanarelloDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.
Andrea QuatranaDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.
Francesca TianoDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0002-2962-981X
Silvia FortuniDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.
Alessandra RufiniDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0001-5654-9615
Florence MalisanDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0002-0213-9407
Roberto TestiDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.
Ivano CondòDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0001-5421-4846
University of Rome Tor Vergata · IT

Funding

University of Rome Tor Vergata NA
6 · The paper itself

Abstract

Friedreich's ataxia (FRDA) is a rare monogenic disease characterized by multisystem, slowly progressive degeneration. Because of the genetic defect in a non-coding region of

Indexed as

Friedreich AtaxiaInterferon-gammaAnimalsAntioxidantsHydrogen PeroxideMiceNF-E2-Related Factor 2Superoxide DismutaseAntioxidantsHydrogen PeroxideInterferon-gammaNF-E2-Related Factor 2Superoxide DismutasecytoprotectionFriedreich’s ataxiainterferon gammaMnSODNrf2

Identifiers

PMID37628866
PMCPMC10454386
OpenAlexW4385760566

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.