Evidence map›Paper›PMID 37628798›Full record

ArticleInternational journal of molecular sciences2023

A Novel Transgenic Mouse Model Implicates

Alexandra V Schmidt, Satdarshan P Monga, Edward V Prochownik, Eric S Goetzman

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alexandra V SchmidtDivision of Genetic and Genomic Medicine, Department of Pediatrics, University of Pittsburgh School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.ORCID 0000-0002-9293-7786
Satdarshan P MongaPittsburgh Liver Research Center, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.ORCID 0000-0002-8437-3378
Edward V ProchownikPittsburgh Liver Research Center, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.ORCID 0000-0001-9666-8205
Eric S GoetzmanDivision of Genetic and Genomic Medicine, Department of Pediatrics, University of Pittsburgh School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.
University of Pittsburgh · US

Funding

Pittsburgh Liver Research CenterP30DK120531 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Shuchang Silvia Liu · 2019 to 2026
$10.9M
Regulation of Peroxisomal Metabolism by Lysine AcylationR01DK090242 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GOETZMAN, ERIC S · 2011 to 2024
$5.4M
Optimizing medium-chain lipids for the treatment of long-chain fatty acid oxidation disordersR01HD103602 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GOETZMAN, ERIC S · 2021 to 2025
$1.7M
NICHD NIH HHS R01 HD103602NIDDK NIH HHS P30 DK120531NIDDK NIH HHS R01 DK090242NIH HHS DK090242
6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer deaths globally. Incidence rates are steadily increasing, creating an unmet need for new therapeutic options. Recently, the inhibition of sirtuin-2 (

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsAnimalsCarcinogensDisease Models, AnimalMiceMice, TransgenicSirtuin 2CarcinogensSirtuin 2c-MYChepatocellular carcinoma (HCC)liversirtuin-2 (Sirt2)transgenic

Identifiers

PMID37628798
PMCPMC10454864
OpenAlexW4385697504

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.