ReviewChildren (Basel, Switzerland)2023
Klippel-Trenaunay Syndrome, Segmental/Focal Overgrowth Malformations: A Review.
Review in Children (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- A 20-year follow-up of a patient with Klippel-Trenaunay syndrome: case report.International journal of surgery case reports · 2026Article
- Dermoscopy and trichoscopy in Klippel-Trénaunay syndrome.Dermatology online journal · 2026Article
- The management of pregnancy for a woman with bilateral Klippel-Trenaunay syndrome: A case report.Case reports in women's health · 2026Article
- Neuraxial Anesthesia in a Parturient With Newly Diagnosed Klippel-Trenaunay Syndrome: A Case Report.Cureus · 2026Article
- Klippel-trenaunay syndrome in a child with coexisting lymphangioma, vascular insufficiency, and multiple soft tissue swellings: a case report.Oxford medical case reports · 2026Article
- Analysis of the application value of endovascular interventional technology in the diagnosis and treatment of vascular malformations with limb hypertrophy.Scientific reports · 2025Article
- A Multi-Institutional Study on the Efficacy and Safety of Wearing a Custom-Made Compression Elastic Garment for 6 Months for Klippel-Trenaunay Syndrome with Venous Malformation.Journal of clinical medicine · 2025Article
- Predominant visceral involvement and heterotopic ossification in Klippel-Trenaunay syndrome.Radiology case reports · 2025Article
- Adult Hip Manifestations in Klippel-Trenaunay Syndrome.Journal of orthopaedic case reports · 2024Article
- A rare case of a 5-year-old girl with Klippel-Trénaunay syndrome and a bleeding focal vulvar hemangioma in Uganda.Clinical case reports · 2024Article
- Value of the short time inversion recovery sequence of magnetic resonance imaging in the staging of Klippel-Trenaunay syndrome complicated with lymphedema.Journal of vascular surgery. Venous and lymphatic disorders · 2024Article
- Surgical Insights and Therapeutic Challenges in the Management of Giant Complex Vascular Malformation of the Buttock.Journal of Indian Association of Pediatric SurgeonsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Klippel-Trenaunay syndrome is an uncommon, infrequent, congenital disorder characterized by a triad of capillary malformation, varicosities, and tissue and bone hypertrophy. The presence of two of these three signs is enough to obtain the diagnosis. Capillary malformations are usually present at birth, whereas venous varicosities and limb hypertrophy become more evident later. The syndrome has usually a benign course, but serious complications involving various organs, such as gastrointestinal and genitourinary organs, as well as the central nervous system, may be observed. Recently, Klippel-Trenaunay syndrome has been included in the group of PIK3CA-related overgrowth spectrum (PROS) disorders. In terms of this disorder, new results in etiopathogenesis and in modalities of treatment have been advanced. We report here a review of the recent genetic findings, the main clinical characteristics and related severe complications, differential diagnoses with a similar disorder, and the management of patients with this complex and uncommon syndrome.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.