Evidence map›Paper›PMID 37628417›Full record

ReviewChildren (Basel, Switzerland)2023

State of the Art Bowel Management for Pediatric Colorectal Problems: Hirschsprung Disease.

Elizaveta Bokova, Ninad Prasade, Sanjana Janumpally, John M Rosen, Irene Isabel P Lim, Marc A Levitt, Rebecca M Rentea

Open access · goldAbstract readReview
In one paragraph

Review in Children (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Observational
  2. Review
  3. Article
  4. Sigmoid Volvulus in Children: A Structured Diagnostic and Therapeutic Approach.Pediatric gastroenterology, hepatology & nutrition · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Controversies in Hirschsprung surgery.World journal of pediatric surgery · 2024
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Elizaveta BokovaComprehensive Colorectal Center, Department of Surgery, Children's Mercy Kansas City, Kansas City, MO 64108, USA.ORCID 0000-0003-0712-3508
Ninad PrasadeComprehensive Colorectal Center, Department of Surgery, Children's Mercy Kansas City, Kansas City, MO 64108, USA.
Sanjana JanumpallyComprehensive Colorectal Center, Department of Surgery, Children's Mercy Kansas City, Kansas City, MO 64108, USA.
John M RosenDivision of Pediatric Gastroenterology, Hepatology and Nutrition, Children's Mercy Kansas City, Kansas City, MO 64108, USA.ORCID 0000-0003-4291-3214
Irene Isabel P LimComprehensive Colorectal Center, Department of Surgery, Children's Mercy Kansas City, Kansas City, MO 64108, USA.ORCID 0000-0002-1711-443X
Marc A LevittDivision of Colorectal and Pelvic Reconstruction, Children's National Medical Center, Washington, DC 20001, USA.ORCID 0000-0002-7711-7392
Rebecca M RenteaComprehensive Colorectal Center, Department of Surgery, Children's Mercy Kansas City, Kansas City, MO 64108, USA.ORCID 0000-0002-8689-5989
Children's Mercy Hospital · USChildren's National · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

After an initial pull-though, patients with Hirschsprung disease (HD) can present with obstructive symptoms, Hirschsprung-associated enterocolitis (HAEC), failure to thrive, or fecal soiling. This current review focuses on algorithms for evaluation and treatment in children with HD as a part of a manuscript series on updates in bowel management. In constipated patients, anatomic causes of obstruction should be excluded. Once anatomy is confirmed to be normal, laxatives, fiber, osmotic laxatives, or mechanical management can be utilized. Botulinum toxin injections are performed in all patients with HD before age five because of the nonrelaxing sphincters that they learn to overcome with increased age. Children with a patulous anus due to iatrogenic damage of the anal sphincters are offered sphincter reconstruction. Hypermotility is managed with antidiarrheals and small-volume enemas. Family education is crucial for the early detection of HAEC and for performing at-home rectal irrigations.

Indexed as

botoxbotulinum toxinbowel managementconstipationenemaenterocolitisfecal incontinenceHirschsprung diseaseirrigationlaxativesobstructiontotal colonic aganglionosis

Identifiers

PMID37628417
PMCPMC10453740
OpenAlexW4386028452

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.