Evidence map›Paper›PMID 37627983›Full record

ArticleFoods (Basel, Switzerland)2023

Metabolomics Profiling of White Button, Crimini, Portabella, Lion's Mane, Maitake, Oyster, and Shiitake Mushrooms Using Untargeted Metabolomics and Targeted Amino Acid Analysis.

Cassi N Uffelman, Katrina A Doenges, Michael L Armstrong, Kevin Quinn, Richard M Reisdorph, Minghua Tang, Nancy F Krebs, Nichole A Reisdorph, Wayne W Campbell

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Domestication Cultivation and Nutritional Analysis ofJournal of fungi (Basel, Switzerland) · 2025
    Article
  5. Lion's Mane Mushroom (Nutrients · 2025
    Review
  6. Comparative Study of Chaga (International journal of molecular sciences · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cassi N UffelmanDepartment of Nutrition Science, Purdue University, West Lafayette, IN 47907, USA.
Katrina A DoengesSkaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Michael L ArmstrongSkaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Kevin QuinnSkaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Richard M ReisdorphSkaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Minghua TangSchool of Medicine, Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Nancy F KrebsSchool of Medicine, Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.ORCID 0000-0001-5652-7547
Nichole A ReisdorphSkaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.ORCID 0000-0002-0425-8012
Wayne W CampbellDepartment of Nutrition Science, Purdue University, West Lafayette, IN 47907, USA.

Funding

Predicting Health Outcomes of Mediterranean Diet via Metabolomics of Foods and BiospecimensR01DK113957 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI CAMPBELL, WAYNE W, KREBS, NANCY F · 2018 to 2022
$3.2M
NIDDK NIH HHS R01 DK113957
6 · The paper itself

Abstract

Mushrooms contain multiple essential nutrients and health-promoting bioactive compounds, including the amino acid L-ergothioneine. Knowledge of the chemical composition of different mushroom varieties will aid research on their health-promoting properties. We compared the metabolomes of fresh raw white button, crimini, portabella, lion's mane, maitake, oyster, and shiitake mushrooms using untargeted liquid chromatography mass spectrometry (LC/MS)-based metabolomics. We also quantified amino acid concentrations, including L-ergothioneine, a potential antioxidant which is not synthesized by plants or animals. Among the seven mushroom varieties, more than 10,000 compounds were detected. Principal Component Analysis indicated mushrooms of the same species,

Indexed as

Agaricus bisporusfood compositionfungiGrifola frondoseHericium erinaceusLentinula edodesL-ergothioneinePleurotus ostreatus

Identifiers

PMID37627983
PMCPMC10453450

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.