ReviewDiagnostics (Basel, Switzerland)2023
Hydroxyapatite Deposition Disease: A Comprehensive Review of Pathogenesis, Radiological Findings, and Treatment Strategies.
Review in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 18 citations in OpenAlex.
- Nucleic Acids as Emerging Regulators of Calcium Phosphate Biomineralization.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Review
- Calcific Tendinitis of the Linea Aspera with Bilateral Deposits and Inflammatory Asymmetry Presenting as Unilateral Pain: A Case Report and Review of Literature.Journal of orthopaedic case reports · 2026Article
- Article
- Recurrent Phosphoglyceride Crystal Deposition Disease in the Mandible Mimicked a Malignant Tumor: Insights from a Clinical Case Report and Literature Review.Diagnostics (Basel, Switzerland) · 2026Article
- Case Report: C-arm-assisted peri-hip endoscopic debridement for calcific tendinitis at the deep insertion of the gluteus maximus.Frontiers in surgery · 2026Article
- Imaging signatures of distinct crystal deposition on high-frequency ultrasound for differentiating gouty arthritis and calcific tendinitis.American journal of translational research · 2026Article
- Calcific Tendinitis: A Pain-Oriented and Site-Specific Narrative Review.Pain research & management · 2026Review
- An Unusual Case of a Mass-Like Hydroxyapatite Deposition Disease Causing Forearm Flexor Tendon Calcific Tendinitis.Case reports in radiology · 2026Article
- Voxel-wise deep learning segmentation of hydroxyapatite and iodine in spectral photon-counting CT: A quantitative phantom study.PloS one · 2026Article
- Ultrasound-Guided Versus Landmark-Based Extracorporeal Shock Wave Therapy for Calcific Shoulder Tendinopathy: An Interventional Clinical Trial.Diagnostics (Basel, Switzerland) · 2025Article
- Calcifications of the Knee's Medial Compartment: A Case Report and Literature Review on the Adductor Magnus Tendon as an Uncommon Location and the Role of Ultrasound-Guided Lavage.Diagnostics (Basel, Switzerland) · 2025Article
- Hydroxyapatite Deposition Disease as Cause of Atraumatic Shoulder Pain: A Case Report.Clinical practice and cases in emergency medicine · 2025Article
- Animal models of tendon calcification: Past, present, and future.Animal models and experimental medicine · 2024Review
- Anakinra for Refractory Pseudogout in Patients with End-stage Renal Disease on Haemodialysis.Mediterranean journal of rheumatology · 2024Article
- Advances in Musculoskeletal Imaging and Their Applications.Journal of clinical medicine · 2023Article
- Imaging findings of acute calcific periarthritis, with emphasis on magnetic resonance imaging: pictorial essay.Radiologia brasileiraArticle
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hydroxyapatite deposition disease (HADD) represents a multifaceted condition characterized by the accumulation of hydroxyapatite crystals in soft tissues, leading to subsequent inflammation and discomfort. The intricate etiology of HADD is the subject of this comprehensive review, which encompasses an in-depth analysis of the four proposed pathogenic mechanisms and a deliberation on the predisposing factors that instigate the development of this disease. In order to provide a thorough understanding of the disease's progression, this manuscript delineates the stages of HADD-those preceding calcification, occurring during calcification, and following calcification-in meticulous detail. This chronology forms the basis of a complete portrayal of the evolution of HADD. Moreover, this review encompasses an examination of the radiological findings associated with HADD, furnishing an extensive discourse on imaging characteristics. The potential of HADD to mimic other diseases, thereby posing diagnostic challenges, is also articulated. The discourse continues with an investigation of HADD's differential diagnosis. This section furnishes a robust framework for distinguishing HADD from other conditions based on imaging results. To enrich the understanding of this diagnostic process, case studies illustrating real-world applications are provided. An overview of treatment modalities for HADD, including both conservative and interventional approaches, forms the concluding discussion. The pivotal role of imaging specialists in the diagnosis and management of HADD is emphasized, highlighting their vital contribution to image-guided procedures and disease monitoring.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.