Evidence map›Paper›PMID 37627885›Full record

ArticleDiagnostics (Basel, Switzerland)2023

B Cell Lymphocytosis in Juvenile Dermatomyositis.

Christopher Costin, Amer Khojah, Elisa Ochfeld, Gabrielle Morgan, Saravanan Subramanian, Marisa Klein-Gitelman, Xiao-Di Tan, Lauren M Pachman

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Christopher CostinDivision of Pediatric Rheumatology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.ORCID 0000-0001-9859-3059
Amer KhojahDepartment of Pediatrics, College of Medicine, Umm Al-Qura University, Makkah 24341-6660, Saudi Arabia.ORCID 0000-0003-3357-4863
Elisa OchfeldDivision of Allergy and Immunology, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Gabrielle MorganDivision of Pediatric Rheumatology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.ORCID 0000-0002-4058-7112
Saravanan SubramanianDepartment of Pediatrics, College of Medicine, University of Illinois Chicago, Chicago, IL 60612, USA.
Marisa Klein-GitelmanDivision of Pediatric Rheumatology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.
Xiao-Di TanDepartment of Pediatrics, College of Medicine, University of Illinois Chicago, Chicago, IL 60612, USA.
Lauren M PachmanDivision of Pediatric Rheumatology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.ORCID 0000-0001-8117-574X
Lurie Children's Hospital · USUniversity of Illinois Chicago · USChildren's Hospital of Philadelphia · USUmm al-Qura University · SA

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
POSTDOCTORAL RHEUMATOLOGY TRAININGT32AR007611 · NIAMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PERLMAN, HARRIS R · 2001 to 2022
$4.4M
Insights into a multi-hit process in the development of necrotizing enterocolitisR01DK129960 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI TAN, XIAO-DI · 2022 to 2025
$2.6M
Mechanisms underlying regulation of intestinal epithelial homeostasis in sepsisR01DK123826 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI TAN, XIAO-DI · 2020 to 2023
$2.4M
Mechanisms of trauma and hemorrhage-induced impairment of innate immunityI01BX001690 · VA · JESSE BROWN VA MEDICAL CENTER · PI TAN, XIAO-DI · 2013 to 2016
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BLRD VA I01 BX001690NCATS NIH HHS UL1 TR001422NIAMS NIH HHS T32 AR007611NIDDK NIH HHS R01 DK123826NIDDK NIH HHS R01 DK129960NIH HHS R01DK123826, R01DK129960, and I01BX001690.NIH HHS UL1TR001422
6 · The paper itself

Abstract

In this study, we determined if B lymphocytosis may serve as a JDM biomarker for disease activity. Children with untreated JDM were divided into two groups based on age-adjusted B cell percentage (determined through flow cytometry): 90 JDM in the normal B cell group and 45 in the high B cell group. We compared through

Indexed as

BAFFB cellbiomarkersjuvenile dermatomyositisneopterinT cell

Identifiers

PMID37627885
PMCPMC10453137
OpenAlexW4385654836

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.