Evidence map›Paper›PMID 37627723›Full record

ArticleAntibiotics (Basel, Switzerland)2023

Regulations on the Use of Antibiotics in Livestock Production in South America: A Comparative Literature Analysis.

Rafael Almeida Da Silva, Nelson Enrique Arenas, Vera Lucia Luiza, Jorge Antonio Zepeda Bermudez, Sian E Clarke

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. High Prevalence of Multidrug-Resistant HaemolyticAntibiotics (Basel, Switzerland) · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Colistin-ResistantAntibiotics (Basel, Switzerland) · 2025
    Article
  15. Foods (Basel, Switzerland) · 2025
    Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rafael Almeida Da SilvaPharmaceutical Assistance Department, Sergio Arouca National School of Public Health, Oswaldo Cruz Foundation, Rio de Janeiro 21040-361, Brazil.ORCID 0000-0002-5049-9124
Nelson Enrique ArenasFaculty of Sciences, Universidad Antonio Nariño, Bogotá 110231, Colombia.ORCID 0000-0002-7665-8955
Vera Lucia LuizaPharmaceutical Assistance Department, Sergio Arouca National School of Public Health, Oswaldo Cruz Foundation, Rio de Janeiro 21040-361, Brazil.
Jorge Antonio Zepeda BermudezPharmaceutical Assistance Department, Sergio Arouca National School of Public Health, Oswaldo Cruz Foundation, Rio de Janeiro 21040-361, Brazil.
Sian E ClarkeDisease Control Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London WC1E 7HT, UK.

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 88887.569864/2020-00National Council for Scientific and Technological Development 140740/2019-8
6 · The paper itself

Abstract

As a global health problem, antimicrobial resistance (AMR) crosses national borders, leading UN (United Nations) multilateral agencies to call for all countries to improve the stewardship of antibiotics in humans and animals. South American countries have changed their regulations regarding antibiotic use in livestock production. This literature review examines how far the five largest meat-producing countries in South America (Argentina, Brazil, Chile, Colombia, and Uruguay) have come in terms of the relevant legislation. Rules on market entry (marketing authorization and official distribution systems) are already set in all countries examined. Four countries do not allow growth promoters based on critically important antibiotics, and countries have also begun to set guidelines and minimum welfare and biosecurity requirements to reduce the therapeutic demand for antibiotics. Nonetheless, there are aspects related to the distribution, use, and disposal of antibiotics that need to be developed further. In conclusion, legislation in South American countries is moving towards the goals set by UN multilateral agencies, but more can be done. Differences between countries' rules and the gold standards set by the World Organization for Animal Health (OIE), World Health Organization (WHO), and Food and Agriculture Organization of the United Nations (FAO) reveal possible adaptations to the countries' realities. Further studies must examine compliance with the legislation already set and investigate other tools that can be used alongside legislation as a driving force to change stakeholder behaviour.

Indexed as

drug resistancelegislationlivestock industrymicrobialOne HealthSouth America

Identifiers

PMID37627723
PMCPMC10451520

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.