Evidence map›Paper›PMID 37627701›Full record

ArticleAntibiotics (Basel, Switzerland)2023

Antibiotic Resistance and Probiotics: Knowledge Gaps, Market Overview and Preliminary Screening.

Gordana Zavišić, Milka Popović, Svetlana Stojkov, Deana Medić, Vera Gusman, Nataša Jovanović Lješković, Aleksandra Jovanović Galović

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Review
  2. Effect of an antibiotic stewardship program on antimicrobial use and resistance in a high prescribing, high resistance setting: A single-center, interrupted time series analysis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Antibiotic Alternatives and Next-Generation Therapeutics forAntibiotics (Basel, Switzerland) · 2025
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gordana ZavišićFaculty of Pharmacy Novi Sad, University Business Academy, Trg Mladenaca 5, 21000 Novi Sad, Serbia.
Milka PopovićDepartment of Hygiene, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21000 Novi Sad, Serbia.ORCID 0000-0003-0647-1308
Svetlana StojkovFaculty of Pharmacy Novi Sad, University Business Academy, Trg Mladenaca 5, 21000 Novi Sad, Serbia.ORCID 0000-0002-4351-332X
Deana MedićDepartment of Microbiology, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21000 Novi Sad, Serbia.
Vera GusmanCenter for Hygiene and Human Ecology, Institute of Public Health of Vojvodina, Futoška 121, 21000 Novi Sad, Serbia.
Nataša Jovanović LješkovićFaculty of Pharmacy Novi Sad, University Business Academy, Trg Mladenaca 5, 21000 Novi Sad, Serbia.
Aleksandra Jovanović GalovićFaculty of Pharmacy Novi Sad, University Business Academy, Trg Mladenaca 5, 21000 Novi Sad, Serbia.ORCID 0000-0002-9488-9781

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Probiotics are among those products, the use of which is increasing, and they are available primarily as food/dietary supplements, as well as in the form of medicines. This study aims to assess the attitudes and practices of health professionals and students of health sciences, give a short overview of the probiotics currently on the market, and conduct a screening of five food supplements and one drug with respect to antibiotic resistance. Nearly half of the respondents in our survey state that probiotics have no side effects, while only 6.3% believe that the use of probiotics can lead to antibiotic resistance. In addition, more than 40% of the participants throw unused probiotics into municipal waste. The market analysis results indicate that probiotic products on the Serbian market have highly variable CFU counts, while the declared health claims cover numerous beneficial health effects, and they are sometimes even registered as medicines. Lactobacilli are frequently present in probiotic supplements, and are sold in pharmacies and online. The experimental results showed that antibiotic resistance is present in different types of lactobacilli in probiotic products. The risk of using probiotics, regardless of their beneficial health effects, should be taken into account in the future. An update to the regulations governing probiotics, including a stipulation for antimicrobial resistance (AMR) testing, should be established, and guidelines for their proper use and disposal put into place.

Indexed as

antibiotic resistanceantibiotic resistance screeningdietary supplementsLactobacillusmarket analysispharmacobioticprobiotic

Identifiers

PMID37627701
PMCPMC10451169

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.