Evidence map›Paper›PMID 37627611›Full record

ArticleAntioxidants (Basel, Switzerland)2023

Peroxiredoxins Play an Important Role in the Regulation of Immunity and Aging in

Olena Odnokoz, Noah Earland, Marziyeh Badinloo, Vladimir I Klichko, Judith Benes, William C Orr, Svetlana N Radyuk

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Olena OdnokozDepartment of Biological Sciences, Southern Methodist University, Dallas, TX 75275, USA.ORCID 0000-0001-6690-7869
Noah EarlandDepartment of Biological Sciences, Southern Methodist University, Dallas, TX 75275, USA.ORCID 0000-0003-0170-407X
Marziyeh BadinlooDepartment of Biological Sciences, Southern Methodist University, Dallas, TX 75275, USA.
Vladimir I KlichkoDepartment of Biological Sciences, Southern Methodist University, Dallas, TX 75275, USA.
Judith BenesDepartment of Biological Sciences, Southern Methodist University, Dallas, TX 75275, USA.
William C OrrDepartment of Biological Sciences, Southern Methodist University, Dallas, TX 75275, USA.
Svetlana N RadyukDepartment of Biological Sciences, Southern Methodist University, Dallas, TX 75275, USA.ORCID 0000-0002-3467-5255
Southern Methodist University · US

Funding

Peroxiredoxins, immune signaling and aging.R01AG032342 · NIA · SOUTHERN METHODIST UNIVERSITY · PI RADYUK, SVETLANA NIKOLAEVNA · 2011 to 2015
$1.5M
NIA NIH HHS R01 AG032342
6 · The paper itself

Abstract

Aberrant immune responses and chronic inflammation can impose significant health risks and promote premature aging. Pro-inflammatory responses are largely mediated via reactive oxygen species (ROS) and reduction-oxidation reactions. A pivotal role in maintaining cellular redox homeostasis and the proper control of redox-sensitive signaling belongs to a family of antioxidant and redox-regulating thiol-related peroxidases designated as peroxiredoxins (Prx). Our recent studies in

Indexed as

agingDrosophilaendoplasmic reticulumimmunitymitochondriaperoxiredoxinreactive oxygen speciesredox state

Identifiers

PMID37627611
PMCPMC10451867
OpenAlexW4385834900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.