Evidence map›Paper›PMID 37627604›Full record

ArticleAntioxidants (Basel, Switzerland)2023

Low Vitamin C Concentrations in Patients with Community-Acquired Pneumonia Resolved with Pragmatic Administration of Intravenous and Oral Vitamin C.

Anitra C Carr, Emma Vlasiuk, Masuma Zawari, Amy Scott-Thomas, Malina Storer, Michael Maze, Stephen T Chambers

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Anitra C CarrDepartment of Pathology and Biomedical Science, University of Otago, Christchurch 8011, New Zealand.ORCID 0000-0002-5890-2977
Emma VlasiukDepartment of Pathology and Biomedical Science, University of Otago, Christchurch 8011, New Zealand.ORCID 0000-0001-7712-5643
Masuma ZawariDepartment of Pathology and Biomedical Science, University of Otago, Christchurch 8011, New Zealand.
Amy Scott-ThomasDepartment of Pathology and Biomedical Science, University of Otago, Christchurch 8011, New Zealand.ORCID 0000-0002-3246-2491
Malina StorerRespiratory Services, Christchurch Hospital, Christchurch 4710, New Zealand.ORCID 0000-0002-7958-0794
Michael MazeRespiratory Services, Christchurch Hospital, Christchurch 4710, New Zealand.
Stephen T ChambersDepartment of Pathology and Biomedical Science, University of Otago, Christchurch 8011, New Zealand.
University of Otago · NZChristchurch Hospital · NZ

Funding

Health Research Council of New Zealand 18/623
6 · The paper itself

Abstract

Community-acquired pneumonia (CAP) is characterized by elevated markers of inflammation and oxidative stress and depleted circulating concentrations of the antioxidant nutrient vitamin C. A feasibility trial of intravenous and oral vitamin C supplementation, matched to the timing of intravenous and oral antibiotic formulations, was carried out and changes in vitamin C status were monitored to determine whether saturating status could be achieved throughout the administration period. Patients with moderate and severe CAP (CURB-65 ≥ 2;

Indexed as

antioxidantascorbic acidcommunity-acquired pneumoniaC-reactive proteininflammationintravenous vitamin Cpneumoniaprocalcitoninvitamin C

Identifiers

PMID37627604
PMCPMC10451831
OpenAlexW4385812502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.