Evidence map›Paper›PMID 37627507›Full record

ReviewAntioxidants (Basel, Switzerland)2023

Total Antioxidant Capacity in Obese and Non-Obese Subjects and Its Association with Anthropo-Metabolic Markers: Systematic Review and Meta-Analysis.

Wendoline Anaya-Morua, José Rafael Villafan-Bernal, Esther Ramírez-Moreno, Humberto García-Ortiz, Raigam Jafet Martínez-Portilla, Cecilia Contreras-Cubas, Angélica Martínez-Hernández, Federico Centeno-Cruz, Florencia Estefana Pedroza-Montoya, Lorena Orozco and 1 more

Abstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Trial
  2. Serum zinc, copper status and Cu/Zn ratio in overweight and obesity: associations with oxidative stress, adipokines, and cardiometabolic traits in adult women.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Article
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  7. Article
  8. Endothelial Progenitor Cells: Disease Markers and Potential Therapy in Kidney Disease.Journal of the American Society of Nephrology : JASN · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Interaction ofAntioxidants (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Wendoline Anaya-MoruaAcademic Area of Medicine, Interdisciplinary Research Center, Institute of Health Sciences, Autonomous University of the State of Hidalgo, Pachuca 42160, Mexico.
José Rafael Villafan-BernalInvestigador por México, Consejo Nacional de Humanidades, Ciencia y Tecnología (CONAHCYT), Mexico City 03940, Mexico.ORCID 0000-0002-6135-4270
Esther Ramírez-MorenoAcademic Area of Nutrition, Interdisciplinary Research Center, Institute of Health Sciences, Autonomous University of the State of Hidalgo, Pachuca 42184, Mexico.ORCID 0000-0002-9928-8600
Humberto García-OrtizImmunogenomics and Metabolic Diseases Laboratory, Instituto Nacional de Medicina Genómica, SS, Mexico City 14610, Mexico.ORCID 0000-0002-0453-980X
Raigam Jafet Martínez-PortillaIberoamerican Research Network in Obstetrics, Gynecology and Translational Medicine, Mexico City 42160, Mexico.
Cecilia Contreras-CubasImmunogenomics and Metabolic Diseases Laboratory, Instituto Nacional de Medicina Genómica, SS, Mexico City 14610, Mexico.
Angélica Martínez-HernándezImmunogenomics and Metabolic Diseases Laboratory, Instituto Nacional de Medicina Genómica, SS, Mexico City 14610, Mexico.
Federico Centeno-CruzImmunogenomics and Metabolic Diseases Laboratory, Instituto Nacional de Medicina Genómica, SS, Mexico City 14610, Mexico.ORCID 0000-0002-3512-4519
Florencia Estefana Pedroza-MontoyaIberoamerican Research Network in Obstetrics, Gynecology and Translational Medicine, Mexico City 42160, Mexico.
Lorena OrozcoImmunogenomics and Metabolic Diseases Laboratory, Instituto Nacional de Medicina Genómica, SS, Mexico City 14610, Mexico.
Francisco Barajas-OlmosImmunogenomics and Metabolic Diseases Laboratory, Instituto Nacional de Medicina Genómica, SS, Mexico City 14610, Mexico.ORCID 0000-0001-5064-6203

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The total antioxidant capacity (TAC) has been related to the development of and complications associated with chronic diseases, but its importance during obesity is not entirely clear. We conducted a systematic review and meta-analysis to clarify whether there are differences or similarities in the TAC between subjects with obesity (SO) and subjects with normal weight (NW). Following the recommendations of PRISMA and Cochrane, we performed a systematic search in the PubMed, Scopus, Web of Science, Cochrane, and PROSPERO databases, identifying 1607 studies. Among these, 22 studies were included in the final analysis, comprising 3937 subjects (1665 SO and 2272 NW) in whom serum TAC was measured, and from these 19,201 subjects, the correlation of serum TAC with anthropo-metabolic parameters was also estimated. The Newcastle-Ottawa method was used for the evaluation of the risk of bias. Using a random-effect model (REM), TAC was reduced in SO independently of age (SMD, -0.86; 95% CI -1.38 to -0.34;

Indexed as

metabolic parametersmetanalysisobesityoxidative stress biomarkerstotal antioxidant capacity

Identifiers

PMID37627507
PMCPMC10451178

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.