Evidence map›Paper›PMID 37627489›Full record

ArticleAntioxidants (Basel, Switzerland)2023

n-3 Polyunsaturated Fatty Acid Supplementation Affects Oxidative Stress Marker Levels in Patients with Type II Intestinal Failure: A Randomized Double Blind Trial.

Adriana Flores-López, Martha Guevara-Cruz, Azalia Avila-Nava, Alejandro G González-Garay, Luis E González-Salazar, Ana L Reyes-Ramírez, José Pedraza-Chaverri, Omar N Medina-Campos, Isabel Medina-Vera, Juan G Reyes-García and 2 more

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 3 pooled it
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 syntheses or guidelines pooled it, 3 citations in OpenAlex.

  1. Comparison of Olive Versus Fish Oil Based Parenteral Nutrition and Clinical Outcomes-A Systematic Review.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Adriana Flores-LópezServicio Nutriología Clínica, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City 14080, Mexico.ORCID 0000-0001-6263-7929
Martha Guevara-CruzDepartamento Fisiología de la Nutrición, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City 14080, Mexico.ORCID 0000-0002-8996-3481
Azalia Avila-NavaUnidad de Investigación, Hospital Regional de Alta Especialidad de la Península de Yucatán, Mérida 97130, Mexico.
Alejandro G González-GarayDepartamento de Metodología de la Investigación, Instituto Nacional de Pediatría, Mexico City 04530, Mexico.
Luis E González-SalazarServicio Nutriología Clínica, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City 14080, Mexico.ORCID 0000-0002-6640-5532
Ana L Reyes-RamírezServicio Nutriología Clínica, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City 14080, Mexico.
José Pedraza-ChaverriDepartamento de Biología, Facultad de Química, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.ORCID 0000-0001-6628-4411
Omar N Medina-CamposDepartamento de Biología, Facultad de Química, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.
Isabel Medina-VeraDepartamento de Metodología de la Investigación, Instituto Nacional de Pediatría, Mexico City 04530, Mexico.ORCID 0000-0003-4027-2329
Juan G Reyes-GarcíaSección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City 11340, Mexico.
Armando R TovarDepartamento Fisiología de la Nutrición, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City 14080, Mexico.ORCID 0000-0002-1292-1312
Aurora E Serralde-ZúñigaServicio Nutriología Clínica, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City 14080, Mexico.ORCID 0000-0001-5579-1450
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán · MXInstituto Nacional de Pediatria · MXUniversidad Nacional Autónoma de México · MXHospital Regional de Alta Especialidad del Bajío · MXInstituto Politécnico Nacional · MX

Funding

Grant "Parenteral Nutrition Research Grant Latin America 2018". Fresenius Kabi. NA
6 · The paper itself

Abstract

Type II intestinal failure (IF-II) is a condition in which the gastrointestinal tract is compromised. Liver complications may occur because of the pathology and/or prolonged use of parenteral nutrition (PN); oxidative stress has been implicated as one of the causes. Lipid emulsions containing n-3 polyunsaturated fatty acids (PUFAs) have been proposed for the treatment. We aimed to evaluate the effect of 7-day n-3 PUFA supplementation on oxidative stress in IF-II patients receiving PN. This was a randomized, controlled, double-blinded, pilot trial of adult patients with IF-II, receiving either conventional PN (control) or PN enriched with n-3 PUFAs (intervention). Twenty patients were included (14 men, 49 ± 16.9 years), with the ANCOVA analysis the glucose (

Indexed as

fish oilintestinal failuren-3 polyunsaturated fatty acidsoxidative stressparenteral nutrition

Identifiers

PMID37627489
PMCPMC10451159
OpenAlexW4385308403

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.