Evidence map›Paper›PMID 37627337›Full record

ArticleBiomolecules2023

Cantharidin-Based Verbenone Derivatives as a Novel Insecticide against

Kwanshik Lee, Hossam Nada, Minkyoung Kim, Hyejun Park, Kiho Lee, Dongho Seo, Kyeong Lee, Yongseok Choi

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Kwanshik LeeCollege of Life Sciences and Biotechnology, Korea University, 145 Anamro, Seungbukgu, Seoul 02841, Republic of Korea.
Hossam NadaCollege of Pharmacy, Dongguk University, 32 Donggukro, Ilsandonggu, Goyangsi 10326, Republic of Korea.ORCID 0000-0002-4882-5621
Minkyoung KimCollege of Pharmacy, Dongguk University, 32 Donggukro, Ilsandonggu, Goyangsi 10326, Republic of Korea.
Hyejun ParkCollege of Life Sciences and Biotechnology, Korea University, 145 Anamro, Seungbukgu, Seoul 02841, Republic of Korea.
Kiho LeeCollege of Pharmacy, Korea University, 2511, Sejongro, Sejong 30019, Republic of Korea.ORCID 0000-0001-6151-6543
Dongho SeoCollege of Pharmacy, Korea University, 2511, Sejongro, Sejong 30019, Republic of Korea.
Kyeong LeeCollege of Pharmacy, Dongguk University, 32 Donggukro, Ilsandonggu, Goyangsi 10326, Republic of Korea.
Yongseok ChoiCollege of Life Sciences and Biotechnology, Korea University, 145 Anamro, Seungbukgu, Seoul 02841, Republic of Korea.
Korea University · KRDongguk University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The diamondback moth is a detrimental insect pest of brassicaceous crops which was among the first crop insects to be reported as DDT resistant. It has since proven to be significantly resistant to nearly every synthetic insecticide used in the field in many crucifer-producing regions. Due to insecticide control failures in some parts of the world, economically viable crucifer production is now all but impossible. As a result, there has been an increasing effort to identify new compounds with strong pesticidal activity. Cantharidin is one such compound that has been shown to be highly effective against a variety of insect pests. However, its chemical synthesis and potential toxicity to non-target organisms have been a major source of concern. Herein, using rational design approaches, a new series of cantharidin-based verbenone derivatives were synthesized and evaluated for their insecticidal activities against the diamondback moth. Among different compounds screened, compounds

Indexed as

InsecticidesBicyclic MonoterpenesCantharidinQuantitative Structure-Activity RelationshipBicyclic MonoterpenesCantharidinInsecticidesverbenone3D QSARcantharidindiamondback mothinsecticidesynthesisverbenone

Identifiers

PMID37627337
PMCPMC10452746
OpenAlexW4386032949

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.