Evidence map›Paper›PMID 37627291›Full record

ArticleBiomolecules2023

Indole-3-Acetamido-Polyamines as Antimicrobial Agents and Antibiotic Adjuvants.

Kenneth Sue, Melissa M Cadelis, Evangelene S Gill, Florent Rouvier, Marie-Lise Bourguet-Kondracki, Jean Michel Brunel, Brent R Copp

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Kenneth SueSchool of Chemical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.ORCID 0000-0002-1477-4117
Melissa M CadelisSchool of Chemical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.ORCID 0000-0003-3883-0109
Evangelene S GillSchool of Chemical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
Florent RouvierMembranes et Cibles Thérapeutiques (MCT), L'Institut National de la Santé et de la Recherche Médicale (INSERM), Aix-Marseille Universite, 27 bd Jean Moulin, 13385 Marseille, France.
Marie-Lise Bourguet-KondrackiLaboratoire Molécules de Communication et Adaptation des Micro-Organismes, UMR 7245 CNRS, Muséum National d'Histoire Naturelle, 57 Rue Cuvier (C.P. 54), 75005 Paris, France.
Jean Michel BrunelMembranes et Cibles Thérapeutiques (MCT), L'Institut National de la Santé et de la Recherche Médicale (INSERM), Aix-Marseille Universite, 27 bd Jean Moulin, 13385 Marseille, France.ORCID 0000-0002-9355-8980
Brent R CoppSchool of Chemical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.ORCID 0000-0001-5492-5269
University of Auckland · NZInserm · FRCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The widespread incidence of antimicrobial resistance necessitates the discovery of new classes of antimicrobials as well as adjuvant molecules that can restore the action of ineffective antibiotics. Herein, we report the synthesis of a new class of indole-3-acetamido-polyamine conjugates that were evaluated for antimicrobial activities against a panel of bacteria and two fungi, and for the ability to enhance the action of doxycycline against

Indexed as

Anti-Infective AgentsFatty Acids, Omega-3Methicillin-Resistant Staphylococcus aureusAdjuvants, ImmunologicAdjuvants, PharmaceuticAnti-Bacterial AgentsDoxycyclineErythromycinEscherichia coliIndolesPolyaminesPseudomonas aeruginosaAdjuvants, ImmunologicAdjuvants, PharmaceuticAnti-Bacterial AgentsAnti-Infective AgentsDoxycyclineErythromycinFatty Acids, Omega-3IndolesPolyaminesantibioticsantifungal agentsantimicrobialindole-3-acetamidepolyaminepotentiatorstructure-activity relationships

Identifiers

PMID37627291
PMCPMC10452110
OpenAlexW4385636572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.