Evidence map›Paper›PMID 37627160›Full record

ArticleCancers2023

Conditional Survival in Prostate Cancer in the Nordic Countries Elucidates the Timing of Improvements.

Frantisek Zitricky, Asta Försti, Akseli Hemminki, Otto Hemminki, Kari Hemminki

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Frantisek ZitrickyBiomedical Center, Faculty of Medicine, Charles University Pilsen, 30605 Pilsen, Czech Republic.
Asta FörstiHopp Children's Cancer Center (KiTZ), 69120 Heidelberg, Germany.ORCID 0000-0002-9857-4728
Akseli HemminkiCancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland.ORCID 0000-0001-7103-8530
Otto HemminkiCancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, 00290 Helsinki, Finland.
Kari HemminkiBiomedical Center, Faculty of Medicine, Charles University Pilsen, 30605 Pilsen, Czech Republic.ORCID 0000-0002-2769-3316
German Cancer Research Center · DEUniversity of Helsinki · FICharles University · CZ

Funding

European Commission 856620
6 · The paper itself

Abstract

backgroundThe incidence of prostate cancer (PC) increased vastly as a result of prostate-specific antigen (PSA) testing. Survival in PC improved in the PSA-testing era, but changes in clinical presentation have hampered the interpretation of the underlying causes.

designWe analyzed survival trends in PC using data from the NORDCAN database for Denmark (DK), Finland (FI), Norway (NO) and Sweden (SE) by analyzing 1-, 5- and 10-year relative survival and conditional relative survival over the course of 50 years (1971-2020).

resultsIn the pre-PSA era, survival improved in FI and SE and improved marginally in NO but not in DK. PSA testing began toward the end of the 1980s; 5-year survival increased by approximately 30%, and 10-year survival improved even more. Conditional survival from years 6 to 10 (5 years) was better than conditional survival from years 2 to 5 (4 years), but by 2010, this difference disappeared in countries other than DK. Survival in the first year after diagnosis approached 100%; by year 5, it was 95%; and by year 10, it was 90% in the best countries, NO and SE.

conclusionsIn spite of advances in diagnostics and treatment, further attention is required to improve PC survival.

Indexed as

periodic survivalprognosisPSA screeningtreatment

Identifiers

PMID37627160
PMCPMC10453103
OpenAlexW4385877534

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.