Evidence map›Paper›PMID 37627140›Full record

ArticleCancers2023

Minimal Residual Disease Detection at RNA and Leukemic Stem Cell (LSC) Levels: Comparison of RT-qPCR, d-PCR and CD26+ Stem Cell Measurements in Chronic Myeloid Leukemia (CML) Patients in Deep Molecular Response (DMR).

Elisabetta Abruzzese, Monica Bocchia, Malgorzata Monika Trawinska, Donatella Raspadori, Francesco Bondanini, Anna Sicuranza, Paola Pacelli, Federica Re, Alessia Cavalleri, Mirko Farina and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Elisabetta AbruzzeseHematology Unit, S. Eugenio Hospital, ASL Roma 2, Tor Vergata University, 00144 Rome, Italy.ORCID 0000-0001-5228-6491
Monica BocchiaChair of Hematology, University of Siena, Azienda Ospedaliera Universitaria, 53100 Siena, Italy.ORCID 0000-0003-3538-3913
Malgorzata Monika TrawinskaHematology Unit, S. Eugenio Hospital, ASL Roma 2, Tor Vergata University, 00144 Rome, Italy.
Donatella RaspadoriChair of Hematology, University of Siena, Azienda Ospedaliera Universitaria, 53100 Siena, Italy.ORCID 0000-0002-2597-6312
Francesco BondaniniLaboratory Medicine Unit, S. Eugenio Hospital, ASL Roma 2, 00144 Rome, Italy.
Anna SicuranzaChair of Hematology, University of Siena, Azienda Ospedaliera Universitaria, 53100 Siena, Italy.ORCID 0000-0002-5840-2956
Paola PacelliChair of Hematology, University of Siena, Azienda Ospedaliera Universitaria, 53100 Siena, Italy.ORCID 0000-0001-5838-1123
Federica ReBone Marrow Transplant Unit, ASST-Spedali Civili di Brescia, Chair of Hematology, Department of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy.ORCID 0000-0003-4219-8695
Alessia CavalleriBone Marrow Transplant Unit, ASST-Spedali Civili di Brescia, Chair of Hematology, Department of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy.
Mirko FarinaBone Marrow Transplant Unit, ASST-Spedali Civili di Brescia, Chair of Hematology, Department of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy.
Michele MalagolaBone Marrow Transplant Unit, ASST-Spedali Civili di Brescia, Chair of Hematology, Department of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy.
Domenico RussoBone Marrow Transplant Unit, ASST-Spedali Civili di Brescia, Chair of Hematology, Department of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy.
Paolo De FabritiisHematology Unit, S. Eugenio Hospital, ASL Roma 2, Tor Vergata University, 00144 Rome, Italy.
Simona BernardiBone Marrow Transplant Unit, ASST-Spedali Civili di Brescia, Chair of Hematology, Department of Clinical and Experimental Sciences, University of Brescia, 25123 Brescia, Italy.ORCID 0000-0002-3494-2624
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITASL Roma · ITUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A Deep Molecular Response (DMR), defined as a

Indexed as

BCR::ABL1CD26chronic myeloid leukemiadigital PCRleukemic stem cellsminimal residual diseaseRT-qPCR

Identifiers

PMID37627140
PMCPMC10452239
OpenAlexW4385835302

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.