Evidence map›Paper›PMID 37626906›Full record

ArticleCells2023

Variable Cre Recombination Efficiency in Placentas of Cyp19-Cre ROSA

Prashanth Anamthathmakula, Philemon D Shallie, Neha Nayak, Sabita Dhal, Jay L Vivian, Gil Mor, Michael J Soares, Nihar R Nayak

Open access · goldAbstract read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Cited2 is a key regulator of placental development and plasticity.BioEssays : news and reviews in molecular, cellular and developmental biology · 2024
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Prashanth AnamthathmakulaDepartment of Obstetrics and Gynecology, University of Missouri-Kansas City School of Medicine, Kansas City, MO 64108, USA.ORCID 0000-0002-0664-9746
Philemon D ShallieDepartment of Obstetrics and Gynecology, University of Missouri-Kansas City School of Medicine, Kansas City, MO 64108, USA.
Neha NayakDepartment of Obstetrics and Gynecology, University of Missouri-Kansas City School of Medicine, Kansas City, MO 64108, USA.
Sabita DhalDepartment of Obstetrics and Gynecology, University of Missouri-Kansas City School of Medicine, Kansas City, MO 64108, USA.
Jay L VivianChildren's Mercy Research Institute, Children's Mercy, Kansas City, MO 64108, USA.
Gil MorC.S. Mott Center for Human Growth and Development, Department of Obstetrics and Gynecology, Wayne State University, Detroit, MI 48201, USA.ORCID 0000-0002-5499-3912
Michael J SoaresInstitute for Reproductive and Developmental Sciences, Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS 66160, USA.
Nihar R NayakDepartment of Obstetrics and Gynecology, University of Missouri-Kansas City School of Medicine, Kansas City, MO 64108, USA.
University of Missouri–Kansas City · USWayne State University · USMercy Research · USUniversity of Kansas Medical Center · US

Funding

Using PCORnet to Expand the DS-CONNECT Cohort Through Healthcare System Recruitment, Incorporating Electronic Health Records, and Assessing Self-DeterminationU54HD090216 · NICHD · UNIVERSITY OF KANSAS LAWRENCE · PI COLOMBO, JOHN A. · 2016 to 2020
$6.2M
VEGF signaling in placental development and diseaseR01HD088549 · NICHD · WAYNE STATE UNIVERSITY · PI NAYAK, NIHAR R · 2017 to 2021
$1.6M
NICHD NIH HHS R01 HD088549
6 · The paper itself

Abstract

The aromatase-Cre recombinase (Cyp19-Cre) transgenic mouse model has been extensively used for placenta-specific gene inactivation. In a pilot study, we observed unexpected phenotypes using this mouse strain, which prompted an extensive characterization of Cyp19-Cre placental phenotypes using ROSA

Indexed as

AnimalsAromataseFemaleIntegrasesMaleMiceMice, TransgenicMosaicismPilot ProjectsPlacentaPlant BreedingPregnancyAromataseCre recombinaseIntegrasesCre inactivationCyp19-Creplacenta

Identifiers

PMID37626906
PMCPMC10453067
OpenAlexW4386030167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.