Evidence map›Paper›PMID 37626901›Full record

ArticleCells2023

TTC6-Mediated Stabilization of the Flagellum Annulus Ensures the Rapid and Directed Motion of Sperm.

Ziqi Wang, Kailun Fang, Yanling Wan, Yingying Yin, Mengjing Li, Ke Xu, Tongtong Li, Yongzhi Cao, Yue Lv, Gang Lu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Loss ofInternational journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Ziqi WangCenter for Reproductive Medicine, Shandong University, Jinan 250012, China.
Kailun FangInstitute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai 200031, China.ORCID 0000-0003-2456-6423
Yanling WanCenter for Reproductive Medicine, Shandong University, Jinan 250012, China.
Yingying YinCenter for Reproductive Medicine, Shandong University, Jinan 250012, China.
Mengjing LiCenter for Reproductive Medicine, Shandong University, Jinan 250012, China.
Ke XuCenter for Reproductive Medicine, Shandong University, Jinan 250012, China.ORCID 0009-0008-4348-6457
Tongtong LiCenter for Reproductive Medicine, Shandong University, Jinan 250012, China.ORCID 0000-0002-1128-4593
Yongzhi CaoCenter for Reproductive Medicine, Shandong University, Jinan 250012, China.
Yue LvCUHK-SDU Joint Laboratory on Reproductive Genetics, School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.ORCID 0000-0003-0913-3662
Gang LuCenter for Reproductive Medicine, Shandong University, Jinan 250012, China.
Hongbin LiuCenter for Reproductive Medicine, Shandong University, Jinan 250012, China.ORCID 0000-0003-2550-7492
Tao HuangCenter for Reproductive Medicine, Shandong University, Jinan 250012, China.ORCID 0000-0002-7086-570X
Shandong University · CNChinese Academy of Sciences · CNChinese University of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sperm motility and structural integrity are essential for successful fertilization in vivo, and any hindrance of the correct assembly of the axoneme and peri-axonemal structures in the sperm flagellum can lead to fertility problems. While there has been considerable advancement in studying diseases related to the flagellum, the underlying mechanisms that control sperm movement are not yet fully understood. In this study, we reveal that the tetratricopeptide repeat protein 6 (

Indexed as

SemenSperm MotilityAnimalsFlagellaMaleMiceSpermatozoaSperm TailannulusflagellumspermsubfertilityTTC6

Identifiers

PMID37626901
PMCPMC10453820
OpenAlexW4385994885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.