Evidence map›Paper›PMID 37626819›Full record

ReviewBiomedicines2023

Decoding the Postulated Entourage Effect of Medicinal

Catalina Christensen, Martin Rose, Claus Cornett, Morten Allesø

Abstract readReview
In one paragraph

Review in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Subchronic Exposure to Low-Dose Cannabidiol (CBD) and ΔPathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Article
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  5. Article
  6. Article
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  8. Article
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  15. Article
  16. Is There a Place for Cannabinoids in Asthma Treatment?International journal of molecular sciences · 2025
    Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Catalina ChristensenTetra Pharm Technologies ApS, Rugmarken 10, DK-3650 Ølstykke, Denmark.ORCID 0009-0002-9823-400X
Martin RoseTetra Pharm Technologies ApS, Rugmarken 10, DK-3650 Ølstykke, Denmark.ORCID 0000-0003-1246-5094
Claus CornettDepartment of Pharmacy, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark.ORCID 0000-0001-6991-5362
Morten AllesøTetra Pharm Technologies ApS, Rugmarken 10, DK-3650 Ølstykke, Denmark.ORCID 0009-0000-2965-5404

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 'entourage effect' term was originally coined in a pre-clinical study observing endogenous bio-inactive metabolites potentiating the activity of a bioactive endocannabinoid. As a hypothetical afterthought, this was proposed to hold general relevance to the usage of products based on

Indexed as

active pharmaceutical ingredientantagonismbioenhancercannabinoidsdrug–drug interactionentourage effectmedicinal cannabispolypharmacologypolypharmacysynergy

Identifiers

PMID37626819
PMCPMC10452568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.