Evidence map›Paper›PMID 37626651›Full record

ArticleBiomedicines2023

Plasma Somatostatin Levels Increase during Scoliosis Surgery, but Not Herniated Disc Operations: Results of a Pilot Study.

Balázs Sütő, Bálint Kolumbán, Éva Szabó, Sára Pásztor, Timea Németh, Teréz Bagoly, Bálint Botz, Erika Pintér, Zsuzsanna Helyes

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Balázs SütőDepartment of Anaesthesia and Intensive Therapy, Medical School, University of Pécs, 7624 Pécs, Hungary.
Bálint KolumbánDepartment of Neurosurgery, Medical School, University of Pécs, 7623 Pécs, Hungary.
Éva SzabóDepartment of Otorhinolaryngology, Medical School, University of Pécs, 7621 Pécs, Hungary.
Sára PásztorDepartment of Internal Medicine, Fejér County Szent György University Teaching Hospital, 8000 Székesfehérvár, Hungary.
Timea NémethDepartment of Languages for Biomedical Purposes and Communication, Medical School, University of Pécs, 7624 Pécs, Hungary.ORCID 0000-0003-4098-190X
Teréz BagolyDepartment of Pharmacology and Pharmacotherapy & Eötvös Loránd Research Network, Chronic Pain Research Group, Medical School, University of Pécs, 7624 Pécs, Hungary.
Bálint BotzDepartment of Pharmacology and Pharmacotherapy & Eötvös Loránd Research Network, Chronic Pain Research Group, Medical School, University of Pécs, 7624 Pécs, Hungary.
Erika PintérDepartment of Pharmacology and Pharmacotherapy & Eötvös Loránd Research Network, Chronic Pain Research Group, Medical School, University of Pécs, 7624 Pécs, Hungary.ORCID 0000-0001-9898-632X
Zsuzsanna HelyesDepartment of Pharmacology and Pharmacotherapy & Eötvös Loránd Research Network, Chronic Pain Research Group, Medical School, University of Pécs, 7624 Pécs, Hungary.
University of Pecs · HUFejér Megyei Szent György Egyetemi Oktató Kórház · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Somatostatin (SST) released from capsaicin-sensitive sensory nerves in response to stimulation exerts systemic anti-inflammatory, analgesic actions. Its elevation correlates with the extent of tissue injury. We measured plasma SST alterations during spine operations (scoliosis and herniated disc) to determine whether its release might be a general protective mechanism during painful conditions. Sampling timepoints were baseline (1), after: soft tissue retraction (2), osteotomy (3), skin closure (4), the following morning (5). Plasma SST-like immunoreactivity (SST-LI) determined by radioimmunoassay was correlated with pain intensity and the correction angle (Cobb angle). In scoliosis surgery, postoperative pain intensity (VAS 2.) 1 day after surgery significantly increased (from 1.44 SEM ± 0.68 to 6.77 SEM ± 0.82,

Indexed as

Cobb angleinflammationmicrodiscectomyneuropeptidesorthopedic and neuro-spine surgerypainradioimmunoassayscoliosis and disc herniationtissue damage

Identifiers

PMID37626651
PMCPMC10452449
OpenAlexW4385415302

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.