Evidence map›Paper›PMID 37626223›Full record

ReviewZeitschrift fur Rheumatologie2023

[Can rheuma be scanned? : Review of the current study situation on fluorescence optical imaging].

Stephanie Gabriele Werner, Marina Backhaus, Sarah Ohrndorf

Abstract readEnglish AbstractReview
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In one paragraph

Review in Zeitschrift fur Rheumatologie, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 71% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Stephanie Gabriele WernerRHIO (Rheumatologie, Immunologie, Osteologie) Düsseldorf und RHIO-Forschungsinstitut, Düsseldorf, Deutschland.
Marina BackhausAbteilung für Rheumatologie und Klinische Immunologie, Parkklinik Weißensee, Berlin, Deutschland.
Sarah OhrndorfMedizinische Klinik mit Schwerpunkt Rheumatologie und Klinische Immunologie, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Deutschland. sarah.ohrndorf@charite.de.
Charité - Universitätsmedizin Berlin · DEPark-Klinik Weißensee · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe novel technique of indocyanine green (ICG)-based fluorescence optical imaging (FOI) using the Xiralite® system (Rheumascan) has been the subject of many different studies worldwide since approval for clinical use in the European Union (2009), USA (2014) and Asia. The FOI depicts the disturbed microcirculation in the joints of both hands caused by inflammation.

objectiveThe aim of this article is to provide an overview of the current state of studies on ICG-based FOI in different rheumatologic indications.

methodsA narrative literature review of publications on ICG-based FOI in the diagnosis of various inflammatory rheumatic joint diseases since 2010 is presented, its use in treatment monitoring is explained, and its value in systemic sclerosis is outlined.

resultsIn summary, studies have extensively demonstrated the accuracy of FOI in inflammation detection. Therefore, it can be concluded that FOI is a good supplement to existing imaging modalities. Due to characteristic patterns of both skin and nails, FOI is an indicated procedure especially in psoriatic arthritis and can be very helpful in the diagnostic process in early undifferentiated arthritis. The FOI has shown its usefulness in children (juvenile idiopathic arthritis), for monitoring the course of treatment, and for demonstrating disturbed microcirculation in patients with systemic sclerosis.

conclusionThe presented data imply that FOI should be considered as a valuable complementary imaging tool in the diagnostic algorithm of daily rheumatologic practice, both for diagnosis and for follow-up monitoring. In particular, the automated analyses should be able in the future to objectify measurements of inflammatory activity as well as monitoring the response to treatment.

Indexed as

Indocyanine GreenOptical ImagingRheumatic DiseasesEvidence-Based MedicineHumansMicroscopy, FluorescenceReproducibility of ResultsSensitivity and SpecificityIndocyanine GreenFollow-up monitoringIndocyanine greenInflammation diagnosticsInflammatory rheumatic joint diseasePsoriatic arthritis

Identifiers

PMID37626223
OpenAlexW4386161226

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.