Evidence map›Paper›PMID 37625677›Full record

ArticleActa biomaterialia2023

Cyclic strain of poly (methyl methacrylate) surfaces triggered the pathogenicity of Candida albicans.

Carolina Montoya, Julia Kurylec, Alex Ossa, Santiago Orrego

Abstract read
In one paragraph

Article in Acta biomaterialia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Beyond roughness: Lateral surface architecture drives Candida albicans virulence on denture polymers.Dental materials : official publication of the Academy of Dental Materials · 2026
    Article
  3. Article
  4. Article
  5. Evaluation of Colonization byMaterials (Basel, Switzerland) · 2025
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Carolina MontoyaDepartment of Oral Health Sciences, Kornberg School of Dentistry, Temple University, Philadelphia, PA, United States.
Julia KurylecDepartment of Oral Health Sciences, Kornberg School of Dentistry, Temple University, Philadelphia, PA, United States.
Alex OssaProduction Engineering Department, School of Engineering, Universidad EAFIT, Medellín, Colombia.
Santiago OrregoDepartment of Oral Health Sciences, Kornberg School of Dentistry, Temple University, Philadelphia, PA, United States; Bioengineering Department, College of Engineering, Temple University, Philadelphia, PA, United States. Electronic address: sorrego@temple.edu.

Funding

Effect of piezoelectric charges on oral microbiome modulationR21DE030564 · NIDCR · TEMPLE UNIV OF THE COMMONWEALTH · PI ORREGO, SANTIAGO · 2021 to 2022
$457k
NIDCR NIH HHS R21 DE030564
6 · The paper itself

Abstract

Candida albicans is an opportunistic yeast and the primary etiological factor in oral candidiasis and denture stomatitis. The pathogenesis of C. albicans could be triggered by several variables, including environmental, nutritional, and biomaterial surface cues. Specifically, biomaterial interactions are driven by different surface properties, including wettability, stiffness, and roughness. Dental biomaterials experience repetitive (cyclic) stresses from chewing and biomechanical movements. Pathogenic biofilms are formed over these biomaterial surfaces under cyclic strain. This study investigated the effect of the cyclic strain (deformation) of biomaterial surfaces on the virulence of Candida albicans. Candida biofilms were grown over Poly (methyl methacrylate) (PMMA) surfaces subjected to static (no strain) and cyclic strain with different levels (ε˜

Indexed as

Candida albicansMycosesBiocompatible MaterialsBiofilmsHumansMethacrylatesPolymethyl MethacrylateTranscription FactorsVirulenceBiocompatible MaterialsMethacrylatesPolymethyl MethacrylateTranscription FactorsBiomaterial-microbial interactionsC. albicansCandida pathogenesisCandidiasisCyclic deformationDenture stomatitisOral biofilmsPMMA

Identifiers

PMID37625677
PMCPMC10705016

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.