Evidence map›Paper›PMID 37624957›Full record

ArticleThe Journal of infectious diseases2024

Assessment of Humoral Immune Responses to Repeated Influenza Vaccination in a Multiyear Cohort: A 5-Year Follow-up.

Meng-Hsuan Sung, W Zane Billings, Michael A Carlock, Hannah B Hanley, Justin Bahl, Andreas Handel, Ted M Ross, Ye Shen

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Meng-Hsuan SungDepartment of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, Georgia, United States.ORCID 0009-0000-5768-7489
W Zane BillingsDepartment of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, Georgia, United States.
Michael A CarlockCenter for Vaccines and Immunology, University of Georgia, Athens, Georgia, United States.
Hannah B HanleyCenter for Vaccines and Immunology, University of Georgia, Athens, Georgia, United States.
Justin BahlDepartment of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, Georgia, United States.
Andreas HandelDepartment of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, Georgia, United States.ORCID 0000-0002-4622-1146
Ted M RossCenter for Vaccines and Immunology, University of Georgia, Athens, Georgia, United States.
Ye ShenDepartment of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, Georgia, United States.ORCID 0000-0002-6662-0048
University of Georgia · USCleveland Clinic · US

Funding

COVID Supplement - COMPONENT A OF THE COLLABORATIVE INFLUENZA VACCINE INNOVATION CENTERS (CIVICS) PROGRAM TO DESIGN AND EVALUATE INNOVATIVE INFLUENZA VACCINE APPROACHES,75N93019C00052 · NIAID · UNIVERSITY OF GEORGIA · PI ROSS, TED · 2019 to 2025
$74.6M
NIAID Centers of Excellence for Influenza Research and Response: Universal Influenza Vaccine Research Activities75N93021C00018 · NIAID · UNIVERSITY OF GEORGIA · PI TOMPKINS, S. MARK · 2021 to 2025
$21.6M
Drivers of individual variation in influenza vaccine response and protection from infectionR01AI170116 · NIAID · UNIVERSITY OF CHICAGO · PI Sarah Cobey, John S Tsang · 2022 to 2026
$7.2M
DYNAMICS AND EVOLUTION OF IMMUNE RESPONSES TO INFLUENZA VIRUSESU01AI150747 · NIAID · EMORY UNIVERSITY · PI AHMED, RAFI, ANTIA, RUSTOM NOSHIR · 2020 to 2024
$5.9M
Refining Predictive Models for Neglected and Emerging Infectious DiseasesR35GM146612 · NIGMS · UNIVERSITY OF GEORGIA · PI Ye Shen · 2022 to 2026
$1.9M
HHS 75N93019C00052)NIAID NIH HHS 75N93019C00052NIAID NIH HHS 75N93021C00018NIAID NIH HHS R01 AI170116NIAID NIH HHS U01 AI150747NIGMS NIH HHS R35 GM146612
6 · The paper itself

Abstract

The long-term effects of host factors on vaccine-elicited immune responses have not been well studied, and the interactions of host factors with annual influenza vaccinations are yet to be explored. We analyzed data from a cohort of 386 individuals who received the standard-dose influenza vaccine and enrolled in ≥2 seasons from 2016 to 2020. Our analyses indicated disparate vaccine-elicited immune responses between males and females in adults when they were repeatedly vaccinated for at least 2 seasons. Notably, we found interactive effects between age and body mass index (BMI) on overall immune responses, and between sex at birth and BMI in adults.

Indexed as

Influenza, HumanInfluenza VaccinesAdultAntibodies, ViralFemaleFollow-Up StudiesHemagglutination Inhibition TestsHumansImmunity, HumoralInfant, NewbornMaleVaccinationAntibodies, ViralInfluenza Vaccinescomposite scorehemagglutination inhibition assayinfluenza vaccinemultiyear cohortrepeat vaccination

Identifiers

PMID37624957
PMCPMC10873184
OpenAlexW4386157990

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.